[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections
J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …
years. As this problem grows worse, infections caused by multiple bacteria are expanding …
Antimicrobial peptides: Application informed by evolution
BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
REW Hancock, HG Sahl - Nature biotechnology, 2006 - nature.com
Short cationic amphiphilic peptides with antimicrobial and/or immunomodulatory activities
are present in virtually every life form, as an important component of (innate) immune …
are present in virtually every life form, as an important component of (innate) immune …
Designing antimicrobial peptides: form follows function
CD Fjell, JA Hiss, REW Hancock… - Nature reviews Drug …, 2012 - nature.com
Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …
[HTML][HTML] Mechanisms and consequences of bacterial resistance to antimicrobial peptides
DI Andersson, D Hughes… - Drug Resistance Updates, 2016 - Elsevier
Cationic antimicrobial peptides (AMPs) are an intrinsic part of the human innate immune
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …
The fitness costs of antibiotic resistance mutations
Antibiotic resistance is increasing in pathogenic microbial populations and is thus a major
threat to public health. The fate of a resistance mutation in pathogen populations is …
threat to public health. The fate of a resistance mutation in pathogen populations is …
Experimental evolution
Experimental evolution is the study of evolutionary processes occurring in experimental
populations in response to conditions imposed by the experimenter. This research approach …
populations in response to conditions imposed by the experimenter. This research approach …
Antimicrobial peptides: key components of the innate immune system
M Pasupuleti, A Schmidtchen… - Critical reviews in …, 2012 - Taylor & Francis
Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …
Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health
T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …
The co-evolution of host cationic antimicrobial peptides and microbial resistance
Endogenous cationic antimicrobial peptides (CAMPs) are among the most ancient and
efficient components of host defence. It is somewhat of an enigma that bacteria have not …
efficient components of host defence. It is somewhat of an enigma that bacteria have not …