Interleukin-6: a novel target for cardio-cerebrovascular diseases
JH Su, MY Luo, N Liang, SX Gong, W Chen… - Frontiers in …, 2021 - frontiersin.org
Cardio-Cerebrovascular Disease is a collective term for cardiovascular disease and
cerebrovascular disease, being a serious threat to human health. A growing number of …
cerebrovascular disease, being a serious threat to human health. A growing number of …
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
Vascular inflammation and the renin-angiotensin system
It is now well established that vascular inflammation is an independent risk factor for the
development of atherosclerosis. In otherwise healthy patients, chronic elevations of …
development of atherosclerosis. In otherwise healthy patients, chronic elevations of …
[HTML][HTML] Chronic stress impacts the cardiovascular system: animal models and clinical outcomes
Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …
cardiovascular diseases are among the most important group of psychosomatic diseases …
How much is too much? Interleukin-6 and its signalling in atherosclerosis
H Schuett, M Luchtefeld, C Grothusen… - Thrombosis and …, 2009 - thieme-connect.com
The importance of inflammation as a driver of pathology is no longer confined to
autoimmune and infectious diseases. In line with convincing experimental data as well as …
autoimmune and infectious diseases. In line with convincing experimental data as well as …
Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture
Atherosclerosis is still an important disease. It accounts for 39% of deaths in the UK and 12
million US citizens have atherosclerosis-associated disease. Atherosclerosis may exert …
million US citizens have atherosclerosis-associated disease. Atherosclerosis may exert …
Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications
Growing body of evidence points out the crucial role of ACE2 in preventing atherosclerosis.
However, data on how atherosclerosis affects ACE2 expression in heart and kidney remains …
However, data on how atherosclerosis affects ACE2 expression in heart and kidney remains …
Angiotensin-converting enzyme and vascular remodeling
Vascular remodeling is the result of a close interplay of changes in vascular tone and
structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of …
structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of …
Novel anti-inflammatory therapies for the treatment of atherosclerosis
R Khan, V Spagnoli, JC Tardif, PL L'Allier - Atherosclerosis, 2015 - Elsevier
The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
Interleukin-6 in atherosclerosis: atherogenic or atheroprotective?
AB Reiss, NM Siegart, J De Leon - Clinical Lipidology, 2017 - Taylor & Francis
ABSTRACT Interleukin-6 (IL-6) is a unique pleiotropic cytokine exhibiting both pro-and anti-
inflammatory properties depending on the target cell type. Plasma IL-6 levels are associated …
inflammatory properties depending on the target cell type. Plasma IL-6 levels are associated …