[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

[HTML][HTML] Physiological feelings

EF Pace-Schott, MC Amole, T Aue, M Balconi… - Neuroscience & …, 2019 - Elsevier
The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

Stress, definitions, mechanisms, and effects outlined: Lessons from anxiety

G Fink - Stress: Concepts, cognition, emotion, and behavior, 2016 - Elsevier
The present volume on concepts, cognition, emotion, and behavior, is the first in this new
Handbook series. The purpose of this first chapter is to provide an outline of stress, stress …

Pharmacological treatment of anxiety disorders: the role of the HPA axis

GE Tafet, CB Nemeroff - Frontiers in psychiatry, 2020 - frontiersin.org
Stress in general, and early life stress in particular, has been associated with the
development of anxiety and mood disorders. The molecular, biological and psychological …

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

M Crumeyrolle-Arias, M Jaglin, A Bruneau… - …, 2014 - Elsevier
Background and aims Establishment of the gut microbiota is one of the most important
events in early life and emerging evidence indicates that the gut microbiota influences …

[HTML][HTML] High anxiety trait: a vulnerable phenotype for stress-induced depression

M Weger, C Sandi - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
A great deal of research aims to identify risk factors related to individual vulnerability to
develop stress-induced psychopathologies. Here, we summarize evidence that point at …

[HTML][HTML] Animal models of anxiety disorders and stress

AC Campos, MV Fogaça, DC Aguiar… - Brazilian Journal of …, 2013 - SciELO Brasil
Anxiety and stress-related disorders are severe psychiatric conditions that affect
performance in daily tasks and represent a high cost to public health. The initial observation …

Phasic vs sustained fear in rats and humans: role of the extended amygdala in fear vs anxiety

M Davis, DL Walker, L Miles, C Grillon - Neuropsychopharmacology, 2010 - nature.com
Data will be reviewed using the acoustic startle reflex in rats and humans based on our
attempts to operationally define fear vs anxiety. Although the symptoms of fear and anxiety …

The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology

EI Martin, KJ Ressler, E Binder… - The Psychiatric clinics …, 2009 - pmc.ncbi.nlm.nih.gov
Mood and anxiety disorders are characterized by a variety of neuroendocrine,
neurotransmitter, and neuroanatomical disruptions. Identifying the most functionally relevant …

Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice

NS de León Reyes, PS Díaz, R Nogueira, A Ruiz-Pino… - Cell, 2023 - cell.com
Social preference, the decision to interact with one member of the same species over
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …