Epidemiology of glioblastoma multiforme–literature review

S Grochans, AM Cybulska, D Simińska, J Korbecki… - Cancers, 2022‏ - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

Epidemiologic and molecular prognostic review of glioblastoma

JP Thakkar, TA Dolecek, C Horbinski… - Cancer epidemiology …, 2014‏ - aacrjournals.org
Glioblastoma multiforme (GBM) is the most common and aggressive primary central nervous
system malignancy with a median survival of 15 months. The average incidence rate of GBM …

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

HS Phillips, S Kharbanda, R Chen, WF Forrest… - Cancer cell, 2006‏ - cell.com
Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …

The transcriptional network for mesenchymal transformation of brain tumours

MS Carro, WK Lim, MJ Alvarez, RJ Bollo, X Zhao… - Nature, 2010‏ - nature.com
The inference of transcriptional networks that regulate transitions into physiological or
pathological cellular states remains a central challenge in systems biology. A mesenchymal …

Genetic pathways to glioblastoma: a population-based study

H Ohgaki, P Dessen, B Jourde, S Horstmann… - Cancer …, 2004‏ - aacrjournals.org
We conducted a population-based study on glioblastomas in the Canton of Zurich,
Switzerland (population, 1.16 million) to determine the frequency of major genetic alterations …

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas

H Ohgaki, P Kleihues - Journal of Neuropathology & …, 2005‏ - academic.oup.com
Published data on prognostic and predictive factors in patients with gliomas are largely
based on clinical trials and hospital-based studies. This review summarizes data on …

Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium

ML Bondy, ME Scheurer, B Malmer… - Cancer, 2008‏ - Wiley Online Library
Abstract Epidemiologists in the Brain Tumor Epidemiology Consortium (BTEC) have
prioritized areas for further research. Although many risk factors have been examined over …

Epidemiology of primary brain tumors: current concepts and review of the literature

M Wrensch, Y Minn, T Chew, M Bondy… - Neuro …, 2002‏ - academic.oup.com
The purpose of this review is to provide a sufficiently detailed perspective on epidemiologic
studies of primary brain tumors to encourage multidisciplinary etiologic and prognostic …

Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance

KJ Hatanpaa, S Burma, D Zhao, AA Habib - Neoplasia, 2010‏ - Elsevier
Aberrant epidermal growth factor receptor (EGFR) signaling is common in cancer. Increased
expression of wild type and mutant EGFR is a widespread feature of diverse types of cancer …

Using the molecular classification of glioblastoma to inform personalized treatment

A Olar, KD Aldape - The Journal of pathology, 2014‏ - Wiley Online Library
Glioblastoma is the most common and most aggressive diffuse glioma, associated with short
survival and uniformly fatal outcome, irrespective of treatment. It is characterized by …