Non-destructive monitoring of 3D cell cultures: new technologies and applications

M Cortesi, E Giordano - PeerJ, 2022 - peerj.com
Abstract 3D cell cultures are becoming the new standard for cell-based in vitro research, due
to their higher transferrability toward in vivo biology. The lack of established techniques for …

A review of biosensors and their applications

B Katey, I Voiculescu… - … Open Journal of …, 2023 - asmedigitalcollection.asme.org
This paper reviews sensors with nano-and microscale dimensions used for diverse
biological applications. A biosensor converts biological responses into electrical signals. In …

Real-time measurement of the trans-epithelial electrical resistance in an organ-on-a-chip during cell proliferation

J Liu, W Zhao, M Qin, X Luan, Y Li, Y Zhao, C Huang… - Analyst, 2023 - pubs.rsc.org
The trans-epithelial electrical resistance (TEER) is widely used to quantitatively evaluate
cellular barrier function at the organ level in vitro. The measurement of the TEER in organ-on …

Stretchable impedance electrode array with high durability for monitoring of cells under mechanical and chemical stimulations

AR Kim, SJ Hong, HB Lee, NE Lee - Lab on a Chip, 2025 - pubs.rsc.org
Electrochemical impedance spectroscopy (EIS) serves as a non-invasive technique for
assessing cell status, while mechanical stretching plays a pivotal role in stimulating cells to …

Application of bioelectrical impedance detection techniques: cells and tissues

J Wen, P Wu, J Li, H Xu, Y Li, K Chen, G Li, Z Lv… - Biosensors and …, 2025 - Elsevier
Pathological conditions in organisms often arise from various cellular or tissue
abnormalities, including dysregulation of cell numbers, infections, aberrant differentiation …

Bioimpedance Measurements of Fibrotic and Acutely Injured Lung Tissues

M Mir, J Chen, A Patel, MR Pinezich, MR Hudock… - Acta Biomaterialia, 2025 - Elsevier
In injured and diseased tissues, changes in molecular and cellular compositions, as well as
tissue architecture, lead to alterations in both physiological and physical characteristics …

[HTML][HTML] New microfluidic system for electrochemical impedance spectroscopy assessment of cell culture performance: design and development of new electrode …

A Chmayssem, CE Tanase, N Verplanck, M Gougis… - Biosensors, 2022 - mdpi.com
Electrochemical impedance spectroscopy (EIS) is widely accepted as an effective and non-
destructive method to assess cell health during cell-culture. However, there is a lack of …

Integrating conductive electrodes into hydrogel-based microfluidic chips for real-time monitoring of cell response

A Pourmostafa, A Bhusal, N Haridas Menon… - … in Bioengineering and …, 2024 - frontiersin.org
The conventional real-time screening in organs-on-chips is limited to optical tracking of pre-
tagged cells and biological agents. This work introduces an efficient biofabrication protocol …

Impedance‐based monitoring of titration and neutralization assays with VSV‐G and SARS‐CoV‐2‐spike pseudoviruses

AK Mildner, S Einhauser, S Michaelis… - Applied …, 2024 - Wiley Online Library
Since cell‐based virus neutralization assays are still the gold standard to assess a patient's
immune protection against a given virus, they are of utmost importance for serodiagnosis …

Electrical sensing of single oocytes in microfluidic systems: A mini review

U Schnakenberg, Y Cao - Applied Research, 2024 - Wiley Online Library
The noninvasive and label‐free electrical characterization of single cells is increasingly
gaining interest over the last years. Besides cancer cells, oocytes are in the focus of those …