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Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding
J Sunter, K Gull - Open biology, 2017 - royalsocietypublishing.org
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The
evolutionary pressure associated with establishing and maintaining an infection and …
evolutionary pressure associated with establishing and maintaining an infection and …
Recent advances in chemotherapeutics for leishmaniasis: importance of the cellular biochemistry of the parasite and its molecular interaction with the host
Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …
The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology
The cell cycle is central to understanding fundamental biology of Leishmania, a group of
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …
Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite,
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Ciliary ectosomes: transmissions from the cell's antenna
CR Wood, JL Rosenbaum - Trends in cell biology, 2015 - cell.com
The cilium is the site of function for a variety of membrane receptors, enzymes and signal
transduction modules crucial for a spectrum of cellular processes. Through targeted …
transduction modules crucial for a spectrum of cellular processes. Through targeted …
Leishmania tarentolae: Taxonomic classification and its application as a promising biotechnological expression host
In this review, we summarize the current knowledge concerning the eukaryotic protozoan
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …
Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process
CL Forestier, C Machu, C Loussert, P Pescher… - Cell host & …, 2011 - cell.com
Leishmania donovani causes human visceral leishmaniasis. The parasite infectious cycle
comprises extracellular flagellated promastigotes that proliferate inside the insect vector …
comprises extracellular flagellated promastigotes that proliferate inside the insect vector …
Peptides to tackle leishmaniasis: Current status and future directions
Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …
the pharmaceutical industry. These molecules are currently being used in the development …
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
M Reverte, RO Eren, B Jha, C Desponds… - PLoS …, 2021 - journals.plos.org
The oxidative burst generated by the host immune system can restrict intracellular parasite
entry and growth. While this burst leads to the induction of antioxidative enzymes, the …
entry and growth. While this burst leads to the induction of antioxidative enzymes, the …