Neurodegenerative diseases (NDs) are a heterogeneous group of aging-associated
ailments characterized by interrupting cellular proteostasic machinery and the misfolding of …

As the demographics of the modern world skew older, understanding and mitigating the
effects of aging is increasingly important within biomedical research. Recent studies in …

Spinal muscular atrophy (SMA) is the most common genetic disease affecting infants and
young adults. Due to mutation/deletion of the survival motor neuron (SMN) gene, SMA is …

Farming and pesticide use have been associated with systemic autoimmune diseases, and
while certain organochlorine insecticides and other pesticides are suspected to influence …

Inhibition plays important roles in modulating the neural activities of sensory and motor
systems at different levels from synapses to brain regions. To achieve coordinated …

The aqueous extract of fallen leaves from Fridericia chica (Bonpl.) LG Lohmann is utilized as
a remedy in communities at northern Colombia. Traditional uses include wound healing …

Many microorganisms live and evolve in complex fluids. Examples include mammalian
spermatozoa in cervical mucus, worms (eg, C. elegans) in wet soil, and bacteria (eg, H …

Amyotrophic lateral sclerosis can be caused by abnormal accumulation of TAR DNA-binding
protein 43 (TDP-43) in the cytoplasm of neurons. Here, we use a C. elegans model for TDP …

Identifying the spinal circuits controlling locomotion is critical for unravelling the mechanisms
controlling the production of gaits. Development of the circuits governing left-right …

Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by the loss-of-function
of the survival motor neuron (SMN) gene resulting in muscle atrophy and weakness. There …