Background A growing body of research identifies the harmful effects that adverse childhood
experiences (ACEs; occurring during childhood or adolescence; eg, child maltreatment or …

Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …

Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …

This article provides a review of the magnitude of mental disorders in children and
adolescents from recent community surveys across the world. Although there is substantial …

OBJECTIVE: To provide an overview of the role of anxiety disorders in medical illness.
METHOD: The Anxiety Disorders Association of America held a multidisciplinary conference …

Context The physical health consequences of childhood psychosocial adversities may be as
substantial as the mental health consequences, but whether this is the case remains unclear …

Depression onset peaks during adolescence and young adulthood. Current treatments are
only moderately effective, driving the search for novel pathophysiological mechanisms …

Asthma is a common non-communicable disease, often characterized by activity limitation,
negative effects on social life and relationships, problems with finding and kee** …

OBJECTIVE: Our objectives were (a) to determine which common mental disorders are
associated with asthma in the general population after controlling for age and sex, and (b) to …

BackgroundBackground: Growing evidence from observational studies indicates a high
prevalence of anxiety in asthma. However, prevalence rates of coexisting anxiety symptoms …