Cellular senescence is a critical stress response program implicated in embryonic
development, wound healing, aging, and immunity, and it backs up apoptosis as an ultimate …

Cellular metabolism in hematopoietic stem cells (HSCs) is an area of intense research
interest, but the metabolic requirements of HSCs and their adaptations to their niches during …

INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …

Diapause, a stage-specific developmental arrest, is widely exploited by insects to bridge
unfavorable seasons. Considerable progress has been made in understanding the ecology …

Aging is a nearly inescapable trait among organisms yet lifespan varies tremendously
across different species and spans several orders of magnitude in vertebrates alone. This …

Diapause is a protective mechanism that many organisms deploy to overcome
environmental adversities. Diapause extends lifespan and fertility to enhance the …

During brain development, the sequence of developmental steps and the underlying
transcriptional regulatory logic are largely conserved across species. However, the temporal …

Diapause, a programmed developmental arrest primarily induced by seasonal
environmental changes, is very common in the animal kingdom, and found in vertebrates …

The young African turquoise killifish has a high regenerative capacity, but loses it with
advancing age, adopting several aspects of the limited form of mammalian regeneration. We …

Cellular senescence is a complex multifactorial biological phenomenon that plays essential
roles in aging, and aging-related diseases. During this process, the senescent cells undergo …