Brain function relies on the ability of neurons to communicate with each other. Interneuronal
communication primarily takes place at synapses, where information from one neuron is …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Long-term potentiation (LTP) of synaptic transmission is considered to be a cellular
counterpart of learning and memory. Activation of postsynaptic NMDA type glutamate …

The Ca 2+/Calmodulin (CaM)-dependent protein kinase II (CaMKII) is activated by Ca
2+/CaM, but becomes partially autonomous (Ca 2+-independent) upon autophosphorylation …

Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

Post-translational modifications of connexins play an important role in the regulation of gap
junction and hemichannel permeability. The prerequisite for the formation of functional gap …

Long-term synaptic plasticity requires a mechanism that converts short Ca 2+ pulses into
persistent biochemical signaling to maintain changes in the synaptic structure and function …

The term synapse applies to cellular specializations that articulate the processing of
information within neural circuits by providing a mechanism for the transfer of information …

Gap junctions provide the basis for electrical synapses between neurons. Early studies in
well-defined circuits in lower vertebrates laid the foundation for understanding various …

The appearance of multicellular organisms imposed the development of several
mechanisms for cell-to-cell communication, whereby different types of cells coordinate their …