Use of metatranscriptomics in microbiome research

S Bashiardes… - … and biology insights, 2016 - journals.sagepub.com
The human intestinal microbiome is a microbial ecosystem that expresses as many as 100
times more genes than the human host, thereby constituting an important component of the …

Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

The battle for iron between bacterial pathogens and their vertebrate hosts

EP Skaar - PLoS pathogens, 2010 - journals.plos.org
Iron is a vital nutrient for virtually all forms of life. The requirement for iron is based on its role
in cellular processes ranging from energy generation and DNA replication to oxygen …

Bacterial small RNA regulators: versatile roles and rapidly evolving variations

S Gottesman, G Storz - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Small RNA regulators (sRNAs) have been identified in a wide range of bacteria and found to
play critical regulatory roles in many processes. The major families of sRNAs include true …

[HTML][HTML] Regulatory RNAs in bacteria

LS Waters, G Storz - Cell, 2009 - cell.com
Bacteria possess numerous and diverse means of gene regulation using RNA molecules,
including mRNA leaders that affect expression in cis, small RNAs that bind to proteins or …

Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity

R Sorek, P Cossart - Nature Reviews Genetics, 2010 - nature.com
Transcriptome-wide studies in eukaryotes have been instrumental in the characterization of
fundamental regulatory mechanisms for more than a decade. By contrast, in prokaryotes …

Bacterial antisense RNAs: how many are there, and what are they doing?

MK Thomason, G Storz - Annual review of genetics, 2010 - annualreviews.org
Antisense RNAs encoded on the DNA strand opposite another gene have the potential to
form extensive base-pairing interactions with the corresponding sense RNA. Unlike other …

Elemental economy: microbial strategies for optimizing growth in the face of nutrient limitation

SS Merchant, JD Helmann - Advances in microbial physiology, 2012 - Elsevier
Microorganisms play a dominant role in the biogeochemical cycling of nutrients. They are
rightly praised for their facility for fixing both carbon and nitrogen into organic matter, and …

Mechanism of RNA silencing by Hfq-binding small RNAs

H Aiba - Current opinion in microbiology, 2007 - Elsevier
The stress-induced small RNAs SgrS and RyhB in Escherichia coli form a specific
ribonucleoprotein complex with RNAse E and Hfq resulting in translation inhibition, RNAse …

A single-base resolution map of an archaeal transcriptome

O Wurtzel, R Sapra, F Chen, Y Zhu… - Genome …, 2010 - genome.cshlp.org
Organisms of the third domain of life, the Archaea, share molecular characteristics both with
Bacteria and Eukarya. These organisms attract scientific attention as research models for …