Theoretical and computational studies of dendrimers as delivery vectors

Y Ma - Chemical Society Reviews, 2013 - pubs.rsc.org
It is a great challenge for nanomedicine to develop novel dendrimers with maximum
therapeutic potential and minimum side-effects for drug and gene delivery. As delivery …

Deuteration and polymers: rich history with great potential

L Li, J Jakowski, C Do, K Hong - Macromolecules, 2021 - ACS Publications
Deuterium, a stable hydrogen isotope, has been playing important roles in many scientific
areas, including polymer science. The developments of deuteration science and polymer …

Are structural properties of dendrimers sensitive to the symmetry of branching? Computer simulation of lysine dendrimers

S Falkovich, D Markelov, I Neelov… - The Journal of Chemical …, 2013 - pubs.aip.org
Poly-L-lysine (PLL) dendrimers are promising systems for biomedical applications due to
their biocompatibility. These dendrimers have a specific topology: two spacers of different …

Nanostructure evolution during relaxation from a large step strain in a supramolecular copolymer-based hydrogel: a SANS investigation

CG Wiener, C Wang, Y Liu, RA Weiss, BD Vogt - Macromolecules, 2017 - ACS Publications
The nanostructure changes associated with stress dissipation in a tough, supramolecular
hydrogel were determined by small-angle neutron scattering (SANS) and compared with …

Diffusion NMR study of generation-five PAMAM dendrimer materials

MA Van Dongen, BG Orr… - The Journal of Physical …, 2014 - ACS Publications
Commercial generation-five poly (amidoamine) dendrimer material (G5c) was fractionated
into its major structural components. Monomeric G5 (G5m; 21–30 kDa) was isolated to …

Structural rearrangement and stiffening of hydrophobically modified supramolecular hydrogels during thermal annealing

C Wang, CG Wiener, Y Yang… - Journal of Polymer …, 2017 - Wiley Online Library
Dynamic crosslinks formed by thermoreversible associations provide an energy dissipation
mechanism to toughen hydrogels. However, the details of the organization of these …

Structured water in polyelectrolyte dendrimers: Understanding small angle neutron scattering results through atomistic simulation

B Wu, B Kerkeni, T Egami, C Do, Y Liu… - The Journal of …, 2012 - pubs.aip.org
Based on atomistic molecular dynamics (MD) simulations, the small angle neutron scattering
(SANS) intensity behavior of a single generation-4 polyelectrolyte polyamidoamine starburst …

Explicit vs implicit water simulations of charged dendrimers

S Huißmann, CN Likos, R Blaak - Macromolecules, 2012 - ACS Publications
Charged dendrimers with terminal or full charge of the nodes, single-or double-spacer, are
simulated and a comparison is made between implicit and explicit water results. The main …

Nanoscopic structural investigation of physically cross-linked nanogels formed from self-associating polymers

Y Sekine, H Endo, H Iwase, S Takeda… - The Journal of …, 2016 - ACS Publications
The detailed structure of a nanogel formed by self-association of cholesterol-bearing
pullulans (CHPs) was determined by contrast variation small-angle neutron scattering. The …

Interactions of PAMAM dendrimers with SDS at the solid–liquid interface

M Yanez Arteta, F Eltes, RA Campbell, T Nylander - Langmuir, 2013 - ACS Publications
This work addresses structural and nonequilibrium effects of the interactions between well-
defined cationic poly (amidoamine) PAMAM dendrimers of generations 4 and 8 and the …