Intriguing of pharmaceutical product development processes with the help of artificial intelligence and deep/machine learning or artificial neural network
N Jariwala, CL Putta, K Gatade, M Umarji… - Journal of Drug Delivery …, 2023 - Elsevier
The objectives of current review are (1) to provide a historical overview of artificial
intelligence and deep/machine learning (AI & D/ML) or Artificial Neural Network (ANN)(2) to …
intelligence and deep/machine learning (AI & D/ML) or Artificial Neural Network (ANN)(2) to …
Quality by design–based development and optimization of fourth-generation ternary solid dispersion of standardized Piper longum extract for melanoma therapy
The study aimed to enhance the solubility, dissolution, and oral bioavailability of
standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary …
standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary …
Intratympanic injections of emulsion-like dispersions to augment cinnarizine amount in a healthy rabbit inner ear model
Aim: To investigate eutectic liquid-based emulsion-like dispersions for intratympanic
injections to augment cinnarizine permeability across round window membrane in a healthy …
injections to augment cinnarizine permeability across round window membrane in a healthy …
Studies on spray dried topical ophthalmic emulsions containing cyclosporin A (0.05% w/w): systematic optimization, in vitro preclinical toxicity and in vivo assessments
Abstract Cyclosporin A (CsA, 0.05% w/w)–loaded positively charged emulsions were
prepared based on castor oil, chitosan, poloxamer 188, glycerin and double-distilled water …
prepared based on castor oil, chitosan, poloxamer 188, glycerin and double-distilled water …
From co-delivery to synergistic anti-inflammatory effect: Studies on chitosan-stabilized Janus emulsions having chloroquine phosphate and flavopiridol in Complete …
For the first time, the co-delivery of chloroquine phosphate and flavopiridol by intra-articular
route was achieved to provide local joint targeting in Complete Freund's Adjuvant-induced …
route was achieved to provide local joint targeting in Complete Freund's Adjuvant-induced …
Development, systematic optimisation and biofilm disruption activity of eugenol-based nanosized emulsions stabilised with Tween 80
The aims of this study were to systematically optimise a formula for eugenol emulsions via
face-centered central composite design and to assess the activity against two-different …
face-centered central composite design and to assess the activity against two-different …
Dual delivery of cyclosporin A and etodolac using polymeric nanocapsules in a rabbit eye model: ocular biodistribution and pharmacokinetic study
Purpose: Commercially available eye drops are loaded only with a single drug. By using the
polymeric nanocapsules, dual delivery of 0.05% w/w cyclosporin A (CsA) and 0.2% w/w …
polymeric nanocapsules, dual delivery of 0.05% w/w cyclosporin A (CsA) and 0.2% w/w …
Cyclosporine release and distribution in ophthalmic emulsions determined by pulsatile microdialysis
An in vitro release test based on pulsatile microdialysis (PMD) is presented for the purpose
of measuring the release of cyclosporine from ophthalmic emulsions, along with a method to …
of measuring the release of cyclosporine from ophthalmic emulsions, along with a method to …
Application of design of experiments® approach-driven artificial intelligence and machine learning for systematic optimization of reverse phase high performance …
The objectives of current investigation are (1) to find out wavelength of maximum
absorbance (λmax) for combined cyclosporin A and etodolac solution followed by selection …
absorbance (λmax) for combined cyclosporin A and etodolac solution followed by selection …
Analytical Quality-by-Design-Based Systematic Optimization of RP-HPLC Method Conditions to Analyze Simultaneously Chloroquine Phosphate and Flavopiridol in …
A design of experiments (DoE)-driven RP-HPLC method conditions was employed to
analyze simultaneously chloroquine (CQ) phosphate and flavopiridol (FLAP) in emulsions …
analyze simultaneously chloroquine (CQ) phosphate and flavopiridol (FLAP) in emulsions …