A new perspective of the hippocampus in the origin of exercise–brain interactions
C Rendeiro, JS Rhodes - Brain Structure and Function, 2018 - Springer
Exercising regularly is a highly effective strategy for maintaining cognitive health throughout
the lifespan. Over the last 20 years, many molecular, physiological and structural changes …
the lifespan. Over the last 20 years, many molecular, physiological and structural changes …
Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery
KM Kantak - Pharmacology Biochemistry and Behavior, 2022 - Elsevier
There are over twenty rodent models of Attention-Deficit Hyperactivity Disorder (ADHD), with
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …
Hormones and the evolution of complex traits: insights from artificial selection on behavior
Although behavior may often be a fairly direct target of natural or sexual selection, it cannot
evolve without changes in subordinate traits that cause or permit its expression. In principle …
evolve without changes in subordinate traits that cause or permit its expression. In principle …
Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: results from an artificial selection experiment
We evaluated the effect of voluntary exercise on spontaneous physical activity (SPA) and
food consumption in mice from 4 replicate lines bred for 57 generations for high voluntary …
food consumption in mice from 4 replicate lines bred for 57 generations for high voluntary …
Long-lasting impairments in adult neurogenesis, spatial learning and memory from a standard chemotherapy regimen used to treat breast cancer
The negative impact of chemotherapy on cognitive function in cancer patients has gained
increasing attention in the last decade. Whilst the short-term acute effects on cognition are …
increasing attention in the last decade. Whilst the short-term acute effects on cognition are …
Early life trauma has lifelong consequences for sleep and behavior
Sleep quality varies widely across individuals, especially during normal aging, with impaired
sleep contributing to deficits in cognition and emotional regulation. Sleep can also be …
sleep contributing to deficits in cognition and emotional regulation. Sleep can also be …
Genetic approaches in comparative and evolutionary physiology
JF Storz, JT Bridgham, SA Kelly… - American Journal of …, 2015 - journals.physiology.org
Whole animal physiological performance is highly polygenic and highly plastic, and the
same is generally true for the many subordinate traits that underlie performance capacities …
same is generally true for the many subordinate traits that underlie performance capacities …
Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors
KCNQ/Kv7 channels conduct voltage‐dependent outward potassium currents that potently
decrease neuronal excitability. Heterozygous inherited mutations in their principle subunits …
decrease neuronal excitability. Heterozygous inherited mutations in their principle subunits …
A new mouse model of ADHD for medication development
P Majdak, JR Ossyra, JM Ossyra, AJ Cobert… - Scientific reports, 2016 - nature.com
ADHD is a major societal problem with increasing incidence and a stagnant track record for
treatment advances. A lack of appropriate animal models has partly contributed to the …
treatment advances. A lack of appropriate animal models has partly contributed to the …
An shen ding zhi ling alleviates symptoms of attention deficit hyperactivity disorder via anti-inflammatory effects in spontaneous hypertensive rats
Y Song, H Yuan, T Chen, M Lu, S Lei… - Frontiers in …, 2021 - frontiersin.org
Attention deficit hyperactivity disorder (ADHD) is a childhood-onset chronic neurobehavioral
disorder, with multiple genetic and environmental risk factors. Chronic inflammation may be …
disorder, with multiple genetic and environmental risk factors. Chronic inflammation may be …