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[HTML][HTML] The role of nuclear factor kappa B (NF-κB) in the immune response against parasites
P Bąska, LJ Norbury - Pathogens, 2022 - mdpi.com
The immune system consists of various cells, organs, and processes that interact in a
sophisticated manner to defend against pathogens. Upon initial exposure to an invader …
sophisticated manner to defend against pathogens. Upon initial exposure to an invader …
Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …
propagate and cause fatal diseases. The microbes overpower host immunity at various …
Targeting and activation of macrophages in leishmaniasis. A focus on iron oxide nanoparticles
Macrophages play a pivotal role as host cells for Leishmania parasites, displaying a notable
functional adaptability ranging from the proinflammatory, leishmanicidal M1 phenotype to …
functional adaptability ranging from the proinflammatory, leishmanicidal M1 phenotype to …
In vitro characterization of Trypanosoma cruzi infection dynamics in skeletal and cardiac myotubes models suggests a potential cell-to-cell transmission in mediating …
JME Contreras-Ortiz… - PLOS Neglected …, 2024 - journals.plos.org
Chagas disease predominantly affects the heart, esophagus, and colon in its chronic phase.
However, the precise infection mechanisms of the causal agent Trypanosoma cruzi in these …
However, the precise infection mechanisms of the causal agent Trypanosoma cruzi in these …
Involvement of Akt and the antiapoptotic protein Bcl‐xL in the inhibition of apoptosis of dendritic cells by Leishmania mexicana
J Rodríguez‐González… - Parasite …, 2022 - Wiley Online Library
The intracellular parasite Leishmania mexicana inhibits camptothecin (CPT)‐induced
apoptosis of monocyte‐derived dendritic cells (moDC) through the down‐regulation of p38 …
apoptosis of monocyte‐derived dendritic cells (moDC) through the down‐regulation of p38 …
The role of NF-κB transcription factor in the regulation of cytokine induced thermal hyperalgesia in a Leishmania major model in BALB/c mice
Cutaneous leishmaniasis caused mainly by Leishmania major (L. major) is one of the
trending models used to investigate induced hyperalgesia and the involved cytokines …
trending models used to investigate induced hyperalgesia and the involved cytokines …
Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds
In the present study, we screened 502 natural product compounds against the in vitro growth
of Babesia (B.) bovis. Then, the novel and potent identified compounds were further …
of Babesia (B.) bovis. Then, the novel and potent identified compounds were further …
Immunomodulators: Progress and prospects in Leishmania infection
Leishmaniasis is a group of tropical infectious diseases that are often overlooked. And
hence is now listed as Neglected Tropical Disease (NTD) under WHO. It is prevalent in 88 …
hence is now listed as Neglected Tropical Disease (NTD) under WHO. It is prevalent in 88 …
Modulation of ERK and AKT pathways as the potential therapeutic targets for Toxoplasma gondii infection
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii, which can infect
humans through oocysts or undercooked meat. It can cause varying symptoms, including …
humans through oocysts or undercooked meat. It can cause varying symptoms, including …
Effect of the cell-growth rate on the invasion and infection efficacy of Trypanosoma cruzi trypomastigotes, and the potential cell-to-cell transfer of the parasite
E Escabia Herrando - 2022 - diva-portal.org
Recent studies proposed that mammalian cell lines with slower growth rates were infected
more efficiently by Trypanosoma cruzi, and that cell-to-cell transmission could be occurring …
more efficiently by Trypanosoma cruzi, and that cell-to-cell transmission could be occurring …