[HTML][HTML] Targeted therapy for breast cancer: An overview of drug classes and outcomes

AT Jacobs, DM Castaneda-Cruz, MM Rose… - Biochemical …, 2022 - Elsevier
The last 25 years have seen significant growth in new therapeutic options for breast cancer,
termed targeted therapies based on their ability to block specific pathways known to drive …

Circulating tumor cells in precision medicine: challenges and opportunities

B Rupp, H Ball, F Wuchu, D Nagrath… - Trends in pharmacological …, 2022 - cell.com
The mutational and phenotypic landscape of tumors is dynamic, requiring constant
monitoring of cancer patients to provide the most up-to-date and effective care. Circulating …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

Liquid biopsy for human cancer: cancer screening, monitoring, and treatment

H Wang, Y Zhang, H Zhang, H Cao, J Mao, X Chen… - MedComm, 2024 - Wiley Online Library
Currently, tumor treatment modalities such as immunotherapy and targeted therapy have
more stringent requirements for obtaining tumor growth information and require more …

[HTML][HTML] The current state of treatment and future directions in cutaneous malignant melanoma

M Ernst, A Giubellino - Biomedicines, 2022 - mdpi.com
Malignant melanoma is the leading cause of death among cutaneous malignancies. While
its incidence is increasing, the most recent cancer statistics show a small but clear decrease …

[PDF][PDF] Hepatocellular carcinoma–circulating tumor cells expressing PD‐L1 are prognostic and potentially associated with response to checkpoint inhibitors

P Winograd, S Hou, CM Court, YT Lee… - Hepatology …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of mortality. Checkpoint inhibitors of
programmed cell death protein‐1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) have …

[HTML][HTML] Immunotherapy in melanoma: Can we predict response to treatment with circulating biomarkers?

E Splendiani, ZM Besharat, A Covre, M Maio… - Pharmacology & …, 2024 - Elsevier
Melanoma is the most aggressive form of skin cancer, representing approximately 4% of all
cutaneous neoplasms and accounting for up to 80% of deaths. Advanced stages of …

SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy

J Li, A Wuethrich, Z Zhang, J Wang, LL Lin… - Analytical …, 2022 - ACS Publications
Immune checkpoint blockade (ICB) therapy has achieved remarkable success in many
cancers including melanoma. However, ICB therapy benefits only a small proportion of …

Potential non-invasive biomarkers in tumor immune checkpoint inhibitor therapy: response and prognosis prediction

R Song, F Liu, Y **, Y Zhang, L Wang - Biomarker research, 2023 - Springer
Immune checkpoint inhibitors (ICIs) have dramatically enhanced the treatment outcomes for
diverse malignancies. Yet, only 15–60% of patients respond significantly. Therefore …

Detection and clinical significance of circulating tumor cells in colorectal cancer

M Jiang, S **, J Han, T Li, J Shi, Q Zhong, W Li… - Biomarker …, 2021 - Springer
Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …