Adipose organ development and remodeling

S Cinti - Comprehensive Physiology, 2018 - iris.univpm.it
During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Current understanding of the role of nesfatin-1

MA Schalla, A Stengel - Journal of the endocrine society, 2018 - academic.oup.com
Nesfatin-1 was discovered in 2006 and implicated in the regulation of food intake.
Subsequently, its widespread central and peripheral distribution gave rise to additional …

High-resolution mRNA and secretome atlas of human enteroendocrine cells

J Beumer, J Puschhof, J Bauzá-Martinez… - Cell, 2020 - cell.com
Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate
gastrointestinal activity, systemic metabolism, and food intake. Little is known about the …

Stimulation of incretin secreting cells

R Pais, FM Gribble, F Reimann - Therapeutic advances in …, 2016 - journals.sagepub.com
The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon
like peptide-1 (GLP-1) are secreted from enteroendocrine cells in the gut and regulate …

NUCB2/nesfatin-1–Inhibitory effects on food intake, body weight and metabolism

MA Schalla, S Unniappan, NWG Lambrecht, M Mori… - Peptides, 2020 - Elsevier
Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by
nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 …

DPP4 as a potential candidate in cardiovascular disease

SY Chen, XQ Kong, KF Zhang, S Luo… - Journal of …, 2022 - Taylor & Francis
The rising prevalence of cardiovascular disease has become a global health concern. The
occurrence of cardiovascular disease is the result of long-term interaction of many risk …

Nesfatin-1–More than a food intake regulatory peptide

A Stengel - Peptides, 2015 - Elsevier
Nesfatin-1 was discovered a decade ago and despite the fact that it represents just one of a
multitude of food intake-inhibiting factors it received increasing attention. This led to a …

Improvement of blood glucose levels and obesity in mice given aronia juice by inhibition of dipeptidyl peptidase IV and α-glucosidase

T Yamane, M Kozuka, D Konda, Y Nakano… - The Journal of nutritional …, 2016 - Elsevier
Aronia berries have many potential effects on health. Previous human studies have shown
that aronia juice may be useful for treatment of obesity disorders. Recently, we have …

Intestinal NUCB2/nesfatin-1 regulates hepatic glucose production via the MC4R-cAMP-GLP-1 pathway

S Geng, S Yang, X Tang, S Xue, K Li, D Liu… - The EMBO …, 2025 - embopress.org
Communication of gut hormones with the central nervous system is important to regulate
systemic glucose homeostasis, but the precise underlying mechanism involved remain little …

Gonadotropin-releasing hormone, kisspeptin, and gonadal steroids directly modulate nucleobindin-2/nesfatin-1 in murine hypothalamic gonadotropin-releasing …

A Hatef, S Unniappan - Biology of reproduction, 2017 - academic.oup.com
Neuroendocrine regulation of metabolism and reproduction are tightly interlinked. Nesfatin-1
is an 82 amino acid metabolic peptide derived from nucleobindin-2 (NUCB2). NUCB2 …