A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology

Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …

Fungal vaccine development: State of the art and perspectives using Immunoinformatics

MM Inácio, ALE Moreira, VRM Cruz-Leite, K Mattos… - Journal of Fungi, 2023 - mdpi.com
Fungal infections represent a serious global health problem, causing damage to health and
the economy on the scale of millions. Although vaccines are the most effective therapeutic …

In silico design of a broad-spectrum multiepitope vaccine against influenza virus

L Yuan, X Li, M Li, R Bi, Y Li, J Song, W Li… - International Journal of …, 2024 - Elsevier
Influenza remains a global health concern due to its potential to cause pandemics as a
result of rapidly mutating influenza virus strains. Existing vaccines often struggle to keep up …

Immunoinformatics-aided rational design of a multi-epitope vaccine targeting feline infectious peritonitis virus

M Chawla, AF Cuspoca, N Akthar… - Frontiers in Veterinary …, 2023 - frontiersin.org
Feline infectious peritonitis (FIP) is a grave and frequently lethal ailment instigated by feline
coronavirus (FCoV) in wild and domestic feline species. The spike (S) protein of FCoV …

Deciphering the immunogenicity of monkeypox proteins for designing the potential mRNA vaccine

M Shah, S Jaan, M Shehroz, A Sarfraz, K Asad… - ACS …, 2023 - ACS Publications
The Monkeypox virus (MPXV), an orthopox virus, is responsible for monkeypox in humans, a
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …

Metagenomics in the fight against zoonotic viral infections: A focus on SARS-CoV-2 analogues

AK Wani, C Chopra, DS Dhanjal, N Akhtar… - Journal of Virological …, 2024 - Elsevier
Zoonotic viral infections continue to pose significant threats to global public health, as
highlighted by the COVID-19 pandemic caused by the SARS-CoV-2 virus. The emergence …

Reverse vaccinology and immunoinformatics approach to design a chimeric epitope vaccine against Orientia tsutsugamushi

A Dolley, HB Goswami, D Dowerah, U Dey, A Kumar… - Heliyon, 2024 - cell.com
Scrub typhus is a vector-borne infectious disease caused by Orientia tsutsugamushi and it is
reportedly associated with up to 20% of hospitalized cases of febrile illnesses. The major …

[HTML][HTML] Designing and development of efficient multi-epitope-based peptide vaccine candidate against emerging avian rotavirus strains: A vaccinomic approach

M Hasan, S Ahmed, M Imranuzzaman, R Bari… - Journal of Genetic …, 2024 - Elsevier
Background Enteric avian rotavirus (ARV) is the etiological agent of several health problems
that pose a global threat to commercial chickens. Therefore, to avoid these widespread …

In silico design and immunoinformatics analysis of a chimeric vaccine construct based on Salmonella pathogenesis factors

MHJN Abadi, FA Abyaneh, N Zare, J Zamani… - Microbial …, 2023 - Elsevier
Currently, there are two vaccines based on killed and/or weakened Salmonella bacteria, but
no recombinant vaccine is available for preventing or treating the disease. We used an in …

Advancing Vaccine Strategies against Candida Infections: Exploring New Frontiers

G Kaur, S Chawla, P Kumar, R Singh - Vaccines, 2023 - mdpi.com
Candida albicans, along with several non-albicans Candida species, comprise a prominent
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …