Progress in microRNA delivery
Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …
regulation of gene expression by several mechanisms. Activity is primarily through binding …
MicroRNAs in development and disease
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer
Introduction Exosomes are 30-100 nm membrane vesicles of endocytic origin, mediating
diverse biological functions including tumor cell invasion, cell-cell communication and …
diverse biological functions including tumor cell invasion, cell-cell communication and …
miR-214 targets ATF4 to inhibit bone formation
Emerging evidence indicates that microRNAs (miRNAs) have important roles in regulating
osteogenic differentiation and bone formation. Thus far, no study has established the …
osteogenic differentiation and bone formation. Thus far, no study has established the …
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
DW Kufe - Oncogene, 2013 - nature.com
Abstract Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is aberrantly
overexpressed in human breast cancer and other cancers. Historically, much of the early …
overexpressed in human breast cancer and other cancers. Historically, much of the early …
MicroRNAs in regulation of triple-negative breast cancer progression
Purpose Dysregulation of miRNA profile has been associated with a broad spectrum of
cellular processes underlying progression of various human malignancies. Increasing …
cellular processes underlying progression of various human malignancies. Increasing …
Regulation of breast cancer metastasis signaling by miRNAs
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …
Tumor microenvironment differences between primary tumor and brain metastases
B Cacho-Díaz, DR García-Botello… - Journal of Translational …, 2020 - Springer
The present review aimed to discuss contemporary scientific literature involving differences
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …
Mucins: Structural diversity, biosynthesis, its role in pathogenesis and as possible therapeutic targets
SS Dhanisha, C Guruvayoorappan, S Drishya… - Critical reviews in …, 2018 - Elsevier
Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …
barrier for epithelial surface and also execute wide range of other physiological functions …
Circulating microRNAs as specific biomarkers for breast cancer detection
Background We previously showed microRNAs (miRNAs) in plasma are potential
biomarkers for colorectal cancer detection. Here, we aimed to develop specific blood-based …
biomarkers for colorectal cancer detection. Here, we aimed to develop specific blood-based …