Progress in microRNA delivery

Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer

R Singh, R Pochampally, K Watabe, Z Lu, YY Mo - Molecular cancer, 2014 - Springer
Introduction Exosomes are 30-100 nm membrane vesicles of endocytic origin, mediating
diverse biological functions including tumor cell invasion, cell-cell communication and …

miR-214 targets ATF4 to inhibit bone formation

X Wang, B Guo, Q Li, J Peng, Z Yang, A Wang, D Li… - Nature medicine, 2013 - nature.com
Emerging evidence indicates that microRNAs (miRNAs) have important roles in regulating
osteogenic differentiation and bone formation. Thus far, no study has established the …

MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

DW Kufe - Oncogene, 2013 - nature.com
Abstract Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is aberrantly
overexpressed in human breast cancer and other cancers. Historically, much of the early …

MicroRNAs in regulation of triple-negative breast cancer progression

D Piasecka, M Braun, R Kordek, R Sadej… - Journal of cancer …, 2018 - Springer
Purpose Dysregulation of miRNA profile has been associated with a broad spectrum of
cellular processes underlying progression of various human malignancies. Increasing …

Regulation of breast cancer metastasis signaling by miRNAs

BJ Petri, CM Klinge - Cancer and metastasis reviews, 2020 - Springer
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Tumor microenvironment differences between primary tumor and brain metastases

B Cacho-Díaz, DR García-Botello… - Journal of Translational …, 2020 - Springer
The present review aimed to discuss contemporary scientific literature involving differences
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …

Mucins: Structural diversity, biosynthesis, its role in pathogenesis and as possible therapeutic targets

SS Dhanisha, C Guruvayoorappan, S Drishya… - Critical reviews in …, 2018 - Elsevier
Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …

Circulating microRNAs as specific biomarkers for breast cancer detection

EKO Ng, R Li, VY Shin, HC **, CPH Leung, ESK Ma… - PloS one, 2013 - journals.plos.org
Background We previously showed microRNAs (miRNAs) in plasma are potential
biomarkers for colorectal cancer detection. Here, we aimed to develop specific blood-based …