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Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …
Visualizing intermediate stages of viral membrane fusion by cryo-electron tomography
SM Kephart, N Hom, KK Lee - Trends in Biochemical Sciences, 2024 - cell.com
Protein-mediated membrane fusion is the dynamic process where specialized protein
machinery undergoes dramatic conformational changes that drive two membrane bilayers …
machinery undergoes dramatic conformational changes that drive two membrane bilayers …
LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy
Various low-density lipoprotein receptors (LPRs) have been identified as entry factors for
alphaviruses, and structures of the corresponding virion-receptor complexes have been …
alphaviruses, and structures of the corresponding virion-receptor complexes have been …
Advances in computational approaches to structure determination of alphaviruses and flaviviruses using cryo-electron microscopy
Advancements in the field of cryo-electron microscopy (cryo-EM) have greatly contributed to
our current understanding of virus structures and life cycles. In this review, we discuss the …
our current understanding of virus structures and life cycles. In this review, we discuss the …
[HTML][HTML] Formalin and 2.5% Glutaraldehyde/2% Paraformaldehyde in 0.1 M Cacodylate Buffer Inactivation Protocols to Ensure the Proper Fixation of Positive Sense …
LE Panny, AE Piper, CL Gardner, CW Burke - Methods and Protocols, 2024 - mdpi.com
Recommendations released by the CDC in 2023 address the need to demonstrate that the
RNA genome of positive-strand RNA viruses is inactivated in addition to viral particles. This …
RNA genome of positive-strand RNA viruses is inactivated in addition to viral particles. This …
Evolution of antiviral resistance captures a transient interdomain functional interaction between chikungunya virus envelope glycoproteins
L Battini, SA Thannickal, MT Cibello, M Bollini… - bioRxiv, 2024 - biorxiv.org
Envelope proteins drive virus and host-cell membrane fusion to achieve virus entry.
Fusogenic proteins are classified into structural classes that function with remarkable …
Fusogenic proteins are classified into structural classes that function with remarkable …
Application of Cryoelectron Microscopy in Antiviral Research
P Narula, MK Lokshman, M Banerjee - Advances in Antiviral Research, 2024 - Springer
In the last decade, single-particle reconstruction from cryoelectron micrographs has been
established as a powerful technique for generating high-resolution structures of biological …
established as a powerful technique for generating high-resolution structures of biological …