The crown and the scepter: roles of the protein corona in nanomedicine

R Cai, C Chen - Advanced Materials, 2019 - Wiley Online Library
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …

Cellular toxicity and immunological effects of carbon-based nanomaterials

X Yuan, X Zhang, L Sun, Y Wei, X Wei - Particle and fibre toxicology, 2019 - Springer
Background Carbon nanomaterials are a growing family of materials featuring unique
physicochemical properties, and their widespread application is accompanied by increasing …

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

F Chen, G Wang, JI Griffin, B Brenneman… - Nature …, 2017 - nature.com
When nanoparticles are intravenously injected into the body, complement proteins deposit
on the surface of nanoparticles in a process called opsonization. These proteins prime the …

Superhydrophobic hemostatic nanofiber composites for fast clotting and minimal adhesion

Z Li, A Milionis, Y Zheng, M Yee, L Codispoti… - Nature …, 2019 - nature.com
Hemostatic materials are of great importance in medicine. However, their successful
implementation is still challenging as it depends on two, often counteracting, attributes; …

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

C Corbo, R Molinaro, A Parodi… - …, 2016 - Taylor & Francis
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

Drug delivery with carbon-based nanomaterials as versatile nanocarriers: progress and prospects

SK Debnath, R Srivastava - Frontiers in Nanotechnology, 2021 - frontiersin.org
With growing interest, a large number of researches have been conducted on carbon-based
nanomaterials (CBNs). However, their uses are limited due to comprehensive potential …

The role of nanotechnology in the treatment of viral infections

L Singh, HG Kruger, GEM Maguire… - Therapeutic …, 2017 - journals.sagepub.com
Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Biomolecular coronas provide the biological identity of nanosized materials

MP Monopoli, C Aberg, A Salvati… - Nano-Enabled Medical …, 2020 - taylorfrancis.com
Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …

Nanofibrous hemostatic materials: Structural design, fabrication methods, and hemostatic mechanisms

X Lu, X Li, J Yu, B Ding - Acta Biomaterialia, 2022 - Elsevier
Abstract Development of rapid and effective hemostatic materials has always been the focus
of research in the healthcare field. Nanofibrous materials which recapitulate the delicate …

Nanoparticles and innate immunity: new perspectives on host defence

D Boraschi, P Italiani, R Palomba, P Decuzzi… - Seminars in …, 2017 - Elsevier
The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …