Recent advances in methods for quantifying the cell penetration of macromolecules

N Batistatou, JA Kritzer - Current Opinion in Chemical Biology, 2024 - Elsevier
As the landscape of macromolecule therapeutics advances, drug developers are continuing
to aim at intracellular targets. To activate, inhibit, or degrade these targets, the …

Applications of vesicle-based artificial cells in analytical chemistry: A review

L Wang, X Zeng, W Shen, S Tang, HK Lee - TrAC Trends in Analytical …, 2023 - Elsevier
Artificial cells have similar morphological characteristics as natural ones and can mimic
many functions of the latter. Artificial cells constructed with liposomes and vesicles have …

Molecular and colloidal self-assembly at the oil–water interface

G Li, YY Zuo - Current Opinion in Colloid & Interface Science, 2022 - Elsevier
Self-assembly is a versatile bottom-up approach for fabricating novel supramolecular
materials with well-defined nano-or micro-structures associated with functionalities. The oil …

Droplet Polymer Bilayers for Bioelectronic Membrane Interfacing

EA Schafer, JJ Maraj, C Kenney… - Journal of the …, 2024 - ACS Publications
Model membranes interfaced with bioelectronics allow for the exploration of fundamental
cell processes and the design of biomimetic sensors. Organic conducting polymers are an …

Liquid-liquid reactions performed by cellular reactors

J Cao, S Tao - Nature Communications, 2024 - nature.com
Liquid-liquid reactions play a significant role in organic synthesis. However, control of the
phase interface between incompatible two-phase liquids remains challenging. Moreover …

High-throughput single biomarker identification using droplet nanopore

LL Zhang, CB Zhong, TJ Huang, LM Zhang, F Yan… - Chemical …, 2024 - pubs.rsc.org
Biomarkers are present in various metabolism processes, demanding precise and
meticulous analysis at the single-molecule level for accurate clinical diagnosis. Given the …

Phase transitions of the pulmonary surfactant film at the perfluorocarbon-water interface

G Li, X Xu, YY Zuo - Biophysical journal, 2023 - cell.com
Pulmonary surfactant is a lipid-protein complex that forms a thin film at the air-water surface
of the lungs. This surfactant film defines the elastic recoil and respiratory mechanics of the …

The Role of Lipid Intrinsic Curvature in the Droplet Interface Bilayer

J Gudyka, J Ceja-Vega, M Krmic, R Porteus, S Lee - Langmuir, 2024 - ACS Publications
Model bilayers are constructed from lipids having different intrinsic curvatures using the
droplet interface bilayer (DIB) method, and their static physicochemical properties are …

Thermally-resilient, phase-invertible, ultra-stable all-aqueous compartments by pH-modulated protein colloidal particles

T Zhou, Z Liu, X Ma, C Cen, Z Huang, Y Lu… - Journal of Colloid and …, 2024 - Elsevier
The essence of compartmentalization in cells is the inspiration behind the engineering of
synthetic counterparts, which has emerged as a significant engineering theme. Here, we …

Ion Transport and Membrane Channel Formation Using a Peptidomimetic in Droplet Interface Bilayers

R Paul, D Dutta, MI Wallace, J Dash - Chemical Communications, 2025 - pubs.rsc.org
Herein, we present a synthetic peptidomimetic, TBP2, which forms artificial membrane
channels within Droplet Interface Bilayers (DIBs). Through real-time electrophysiology, TIRF …