Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …

Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

The innate immune system has the capacity to detect 'non-self'molecules derived from
pathogens, known as pathogen-associated molecular patterns, via pattern recognition …

Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Induction of cell death is inexorably linked with cancer therapy, but this can also initiate
wound-healing processes that have been linked to cancer progression and therapeutic …

Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, sha** adaptive and innate immunity. Over the years, a …

A fundamental concept in immunology is that the innate immune system initiates or instructs
downstream adaptive immune responses. Inflammasomes are central players in innate …

Dendritic cells (DCs) play a central role in the regulation of the balance between CD8 T cell
immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 …

It has been a century since the death of Élie Metchnikoff, who championed the role of
phagocytosis in cellular immunity. Whereas others had observed the uptake of particles by …