[HTML][HTML] Graph neural networks in histopathology: Emerging trends and future directions

S Brussee, G Buzzanca, AMR Schrader, J Kers - Medical Image Analysis, 2025 - Elsevier
Histopathological analysis of whole slide images (WSIs) has seen a surge in the utilization
of deep learning methods, particularly Convolutional Neural Networks (CNNs). However …

Next Generation of Colorectal Cancer Management: Integrating Omics, Targeted Therapies, and Smart Technologies

TA Addissouky - Avicenna Journal of Medical Biochemistry, 2024 - ajmb.umsha.ac.ir
Colorectal cancer (CRC) remains a significant global health concern, with increasing
incidence rates observed in young adults and Asian populations. Recent advancements in …

An initial game-theoretic assessment of enhanced tissue preparation and imaging protocols for improved deep learning inference of spatial transcriptomics from tissue …

MY Fatemi, Y Lu, AB Diallo, G Srinivasan… - Briefings in …, 2024 - academic.oup.com
The application of deep learning to spatial transcriptomics (ST) can reveal relationships
between gene expression and tissue architecture. Prior work has demonstrated that inferring …

Potential to enhance large scale molecular assessments of skin photoaging through virtual inference of spatial transcriptomics from routine staining

G Srinivasan, MJ Davis, MR LeBoeuf… - Pacific Symposium …, 2024 - pmc.ncbi.nlm.nih.gov
The advent of spatial transcriptomics technologies has heralded a renaissance in research
to advance our understanding of the spatial cellular and transcriptional heterogeneity within …

Deep topographic proteomics of a human brain tumour

S Davis, C Scott, J Oetjen, PD Charles… - Nature …, 2023 - nature.com
The spatial organisation of cellular protein expression profiles within tissue determines
cellular function and is key to understanding disease pathology. To define molecular …

Identification of novel diagnostic biomarkers associated with liver metastasis in colon adenocarcinoma by machine learning

L Yang, Y Tian, X Cao, J Wang, B Luo - Discover Oncology, 2024 - Springer
Background Liver metastasis is one of the primary causes of poor prognosis in colon
adenocarcinoma (COAD) patients, but there are few studies on its biomarkers. Methods The …

ClinValAI: A framework for develo** Cloud-based infrastructures for the External Clinical Validation of AI in Medical Imaging

OA Ramwala, KP Lowry, DS Hippe… - … 2025: Proceedings of …, 2024 - World Scientific
Artificial Intelligence (AI) algorithms showcase the potential to steer a paradigm shift in
clinical medicine, especially medical imaging. Concerns associated with model …

Enhancing PFI prediction with GDS-MIL: A graph-based dual stream MIL approach

G Bontempo, N Bartolini, M Lovino, F Bolelli… - … Conference on Image …, 2023 - Springer
Abstract Whole-Slide Images (WSI) are emerging as a promising resource for studying
biological tissues, demonstrating a great potential in aiding cancer diagnosis and improving …

Integrative co-registration of elemental imaging and histopathology for enhanced spatial multimodal analysis of tissue sections through TRACE

Y Lu, S Han, A Srivastava, N Shaik… - Bioinformatics …, 2025 - academic.oup.com
Elemental imaging provides detailed profiling of metal bioaccumulation, offering more
precision than bulk analysis by targeting specific tissue areas. However, accurately …

The Overlooked Role of Specimen Preparation in Bolstering Deep Learning-Enhanced Spatial Transcriptomics Workflows

MY Fatemi, Y Lu, AB Diallo, G Srinivasan, ZL Azher… - medRxiv, 2023 - medrxiv.org
The application of deep learning methods to spatial transcriptomics has shown promise in
unraveling the complex relationships between gene expression patterns and tissue …