Central serous chorioretinopathy (CSC) is a common form of vision loss, typically seen in
working-age men. The pathophysiology behind CSC still eludes us, however significant …

The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …

Rationale: Congenital heart disease (CHD) is among the most common birth defects. Most
cases are of unknown pathogenesis. Objective: To determine the contribution of de novo …

Cell-tracing studies in the mouse indicate that the cardiac lineage arises from a population
that expresses the vascular endothelial growth factor receptor 2 (VEGFR2, Flk-1) …

The T-box family transcription factor gene TBX20 acts in a conserved regulatory network,
guiding heart formation and patterning in diverse species. Mouse Tbx20 is expressed in …

The myriad developmental roles served by the T-box family of transcription factor genes defy
easy categorization. Present in all metazoans, the T-box genes are involved in early …

The role of GATA4 during the earliest stages of cardiogenesis has not been defined
because Gata4 knockout embryos suffer an early developmental arrest caused by …

The WGATAR motif is a common nucleotide sequence found in the transcriptional regulatory
regions of numerous genes. In vertebrates, these motifs are bound by one of six factors …

In this review we discuss the major morphogenetic and regulative events that control
myocardial progenitor cells from the time that they delaminate from the epiblast in the …

Objective—Vascular adventitia encompasses progenitors and is getting recognized as the
major site of inflammation in early stage of atherosclerosis. However, the cellular atlas of the …