Supramolecular adhesive hydrogels for tissue engineering applications

Y Zhao, S Song, X Ren, J Zhang, Q Lin… - Chemical …, 2022 - ACS Publications
Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …

Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Porous hydrogels: Present challenges and future opportunities

R Foudazi, R Zowada, I Manas-Zloczower, DL Feke - Langmuir, 2023 - ACS Publications
In this feature article, we critically review the physical properties of porous hydrogels and
their production methods. Our main focus is nondense hydrogels that have physical pores …

Is it time to start transitioning from 2D to 3D cell culture?

C Jensen, Y Teng - Frontiers in molecular biosciences, 2020 - frontiersin.org
Cell culture is an important and necessary process in drug discovery, cancer research, as
well as stem cell study. Most cells are currently cultured using two-dimensional (2D) …

Hydrogel microparticles for biomedical applications

AC Daly, L Riley, T Segura, JA Burdick - Nature Reviews Materials, 2020 - nature.com
Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

A comprehensive review on collagen type I development of biomaterials for tissue engineering: From biosynthesis to bioscaffold

IN Amirrah, Y Lokanathan, I Zulkiflee, MFMR Wee… - Biomedicines, 2022 - mdpi.com
Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …

Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

A hydrogen‐bonded extracellular matrix‐mimicking bactericidal hydrogel with radical scavenging and hemostatic function for pH‐responsive wound healing …

Z Ahmadian, A Correia, M Hasany… - Advanced …, 2021 - Wiley Online Library
Generation of reactive oxygen species, delayed blood clotting, prolonged inflammation,
bacterial infection, and slow cell proliferation are the main challenges of effective wound …

Fundamentals and applications of photo-cross-linking in bioprinting

KS Lim, JH Galarraga, X Cui, GCJ Lindberg… - Chemical …, 2020 - ACS Publications
This review provides a detailed overview of the rapidly advancing field of biofabrication,
particularly with regards to the use of photo-cross-linking (ie, light-based) techniques. The …

Rapid printing of bio-inspired 3D tissue constructs for skin regeneration

F Zhou, Y Hong, R Liang, X Zhang, Y Liao, D Jiang… - Biomaterials, 2020 - Elsevier
It is still a challenge for existing bioprinting technologies to fabricate organs suitable for
implantation, mainly due to the inability to recapitulate the organs' complex anatomical …