▪ Abstract Changes in ploidy occurred early in the diversification of some animal and plant
lineages and represent an ongoing phenomenon in others. While the prevalence of …

REVIEW Most higher organisms reproduce sexually, despite the automatic reproductive
advantage experienced by asexual variants. This implies the operation of selective forces …

Sexual reproduction and recombination are ubiquitous. However, a large body of theoretical
work has shown that these processes should only evolve under a restricted set of conditions …

Recombination is typically thought of as a symmetrical process resulting in large-scale
reciprocal genetic exchanges between homologous chromosomes. Recombination events …

The intron has been a big biological mystery since it was first discovered in several aspects.
First, all of the completely sequenced eukaryotes harbor introns in the genomic structure …

When beneficial mutations are rare, they accumulate by a series of selective sweeps. But
when they are common, many beneficial mutations will occur before any can fix, so there will …

Sexual reproduction entails a number of costs, and yet the majority of eukaryotes engage in
sex, at least occasionally. In this article, I review early models to explain the evolution of sex …

Domestication of plants and animals is the major factor underlying human civilization and is
a gigantic evolutionary experiment of adaptation and speciation, generating incipient …

Observations about the number, frequency, effect size, and genomic distribution of alleles
associated with complex traits must be interpreted in light of evolutionary process. These …

Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. The vaginal
microbiome has been associated with PTB, yet the mechanisms underlying this association …