A common feature of cancer cells is their ability to rewire their metabolism to sustain the
production of ATP and macromolecules needed for cell growth, division and survival. In …

Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

Because more and more men are being diagnosed with prostate cancer worldwide,
knowledge about and prevention of this disease is important. Epidemiological studies have …

Prostate cancer, a leading cause of cancer death, displays a broad range of clinical
behavior from relatively indolent to aggressive metastatic disease. To explore potential …

Background: DD3PCA3 is the most prostate cancer-specific gene described to date. To
assess the clinical utility of DD3PCA3 a time-resolved fluorescence-based, quantitative RT …

Molecular profiling of cancer at the transcript level has become routine. Large-scale analysis
of proteomic alterations during cancer progression has been a more daunting task. Here, we …

This review focuses on new findings and controversial issues in the pathology and
molecular biology of adenocarcinoma of the prostate. Since management of high-grade …

Background New biomarkers, such as autoantibody signatures, may improve the early
detection of prostate cancer. Methods With a phage-display library derived from prostate …

The malignant transformation of cells requires adaptations across multiple metabolic
processes to satisfy the energy required for their increased rate of proliferation …

High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely
preinvasive stage of adenocarcinoma, almost two decades after its first formal description …