Open-shell molecules such as radicals, carbenes, and electronically excited-state molecules
exhibit high energies, and thus, in general, they are quite reactive. 1 The short-lived species …

Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

More than 50 years have passed since Haszeldine reported the first addition of a
trifluoromethyl radical to an allene; in the intervening years, both the chemistry of allenes …

Arynes, which are formally derived from aromatic rings by abstraction of two hydrogen
atoms, have been a focus of organic chemistry for 100 years. In contrast to ortho‐benzyne …

The recent discovery of several potent antiturnor antibiotics containing (Z)-enediynes or
rented systems has pushed the exploration of enediynes to the forefront of chemical and …

The broad utility of cyclic structures accounts for the key roles that cycle-forming reactions
play in synthetic designs. Most of these reactions can be classified as either a cyclization of …

The synergy between bond formation and bond breaking that is typical for pericyclic
reactions is lost in their mechanistic cousins, cycloaromatization reactions. In these …

The C2− C6 (Schmittel)/ene cyclization of enyne-allenes is studied by a combination of
kinetic isotope effects, theoretical calculations, and dynamics trajectories. For the cyclization …

In this work we present a new partitioning scheme for the incremental approach in
combination with the efficient (F12*) approximation for explicitly correlated coupled cluster …

The construction of aromatic rings has become a key objective for organic chemists. While
several strategies have been developed for the functionalization of pre-formed aromatic …