The free radical nitric oxide (NO•) exerts biological effects through the direct and reversible
interaction with specific targets (eg soluble guanylate cyclase) or through the generation of …

Over the past century, HNO research has evolved from fundamental physical examinations
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …

Since 1988, there has been much literature published on the chemistry of nitric oxide,
particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by …

Nitroxyl (HNO), the 1-electron reduced and protonated congener of nitric oxide (NO), has
received recent attention as a potential pharmacological agent for the treatment of heart …

It has been over 15 years since the discovery of endogenous nitric oxide (NO) generation in
mammalian systems (1-3). This was a significant event since it represented a fundamentally …

We describe new developments in the coordination chemistry of bound nitrosyl, considering
its three formal redox states: NO+, NO and NO−/HNO. We emphasize on the correlation …

Recent studies distinguish the biological and pharmacological effects of nitroxyl (HNO) from
its oxidized/deprotonated product nitric oxide (· NO), but the lack of HNO detection methods …

▪ Abstract Recent discoveries of novel and potentially important biological activity have
spurred interest in the chemistry and biochemistry of nitroxyl (HNO). It has become clear that …

Small redox active molecules such as reactive nitrogen and oxygen species and hydrogen
sulfide have emerged as important biological mediators that are involved in various …

The coordination chemistry of the one-electron reduced form of nitric oxide, termed a nitroxyl
or nitrosyl hydride (NO− or HNO), is described with special focus on its interaction with …