Prevention of atherosclerosis is important because it is a risk factor for cardiovascular
diseases globally. One of the causes of atherosclerosis is accumulation of cholesterol and …

A low level of high-density lipoprotein cholesterol (HDL-C) is an important risk factor for
cardiovascular disease. Epidemiological and clinical studies provide evidence that HDL-C …

Partial resistance of cell membranes to solubilization with mild detergents and the analysis
of isolated detergent-resistant membranes (DRMs) have been used operationally to define …

Analysis of free cholesterol (FC) is not well suited for electrospray ionization (ESI); however,
cholesteryl ester (CE) form ammonium adducts in positive ion mode and generate a …

Blood high-density lipoprotein (HDL) levels are inversely related to risk for cardiovascular
disease, implying that factors associated with HDL metabolism are atheroprotective. One of …

The removal of excess free cholesterol from cells by HDL or its apolipoproteins is important
for maintaining cellular cholesterol homeostasis. This process is most likely compromised in …

Glycerophospholipid and sphingolipid species and their bioactive metabolites are important
regulators of lipoprotein and cell function. The aim of the study was to develop a method for …

▪ Abstract Considerable evidence shows that lateral inhomogeneities in lipid composition
and physical properties exist in biological membranes. These membrane lipid domains are …

Observational studies provide overwhelming evidence that a low high-density lipoprotein
(HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and …

It is widely believed that HDL protects against atherosclerosis by removing excess
cholesterol from arterial cells. Lipid-poor HDL apolipoproteins promote efflux of cholesterol …