Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …

Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

The tumor microenvironment represents a complex network, in which tumor cells not only
communicate with each other but also with stromal and immune cells. Current research has …

Virtually all cells in the organism secrete extracellular vesicles (EVs), a heterogeneous
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …

Exomeres are a recently discovered type of extracellular nanoparticle with no known
biological function. Herein, we describe a simple ultracentrifugation-based method for …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …