Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …

Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

The inflammatory response and the activation of coagulation are two important responses in
a host's defense against infection. These mechanisms do not work independently, but …

Senescence compromises the essential role that the endothelium plays in maintaining
vascular homeostasis, so promoting endothelial dysfunction and the development of age …

Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs
(miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However …

In the majority of patients with systemic inflammatory conditions, some degree of activation
of coagulation is present. Increasing evidence points to an extensive cross‐talk between …

Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …

Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …

Background. Several studies demonstrated that mesenchymal stem cells (MSCs) reverse
acute kidney injury (AKI) by a paracrine mechanism rather than by MSC transdifferentiation …