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Inflammation and the two-hit hypothesis of schizophrenia
The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …
Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: a systematic review of biomarker studies
The search for immune biomarkers in psychiatric disorders has primarily focused on pro-
inflammatory cytokines. Other immune proteins including chemokines have been relatively …
inflammatory cytokines. Other immune proteins including chemokines have been relatively …
Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG …
Context Evidence for symptomatic convergence of schizophrenia and N-methyl-D-aspartate
glutamate receptor (NMDA-R) encephalitis highlights the need for an assessment of …
glutamate receptor (NMDA-R) encephalitis highlights the need for an assessment of …
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction
We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …
A systematic review of metabolite biomarkers of schizophrenia
Current diagnosis of schizophrenia relies exclusively on the potentially subjective
interpretation of clinical symptoms and social functioning as more objective biological …
interpretation of clinical symptoms and social functioning as more objective biological …
Towards a psychosis risk blood diagnostic for persons experiencing high-risk symptoms: preliminary results from the NAPLS project
Introduction: A barrier to preventative treatments for psychosis is the absence of accurate
identification of persons at highest risk. A blood test that could substantially increase …
identification of persons at highest risk. A blood test that could substantially increase …
Role of inflammation in the pathogenesis of schizophrenia: A review of the evidence, proposed mechanisms and implications for treatment
Aim Over the past several decades, there has been a growing research interest in the role of
inflammation in the pathogenesis of schizophrenia. This review aims to summarize evidence …
inflammation in the pathogenesis of schizophrenia. This review aims to summarize evidence …
Markers of inflammation and stress distinguish subsets of individuals with schizophrenia and bipolar disorder
Schizophrenia and bipolar disorder share a number of common features, both
symptomatically and biologically. Abnormalities in the neuroimmune and the stress …
symptomatically and biologically. Abnormalities in the neuroimmune and the stress …
Innate immune cells and C-reactive protein in acute first-episode psychosis and schizophrenia: relationship to psychopathology and treatment
Innate immunity has been linked to initiation of Alzheimer's disease and multiple sclerosis.
Moreover, risk of first-episode psychosis (FEP) and schizophrenia (Sz) is increased after …
Moreover, risk of first-episode psychosis (FEP) and schizophrenia (Sz) is increased after …
Biomarkers in schizophrenia: A focus on blood based diagnostics and theranostics
CY Lai, E Scarr, M Udawela, I Everall… - World journal of …, 2016 - pmc.ncbi.nlm.nih.gov
Identifying biomarkers that can be used as diagnostics or predictors of treatment response
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …