Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
Serotonin and brain function: a tale of two receptors
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …
achieve consensus. In this present synthesis, we integrate previous perspectives with new …
Sentience in decapod crustaceans: A general framework and review of the evidence
We outline a framework for evaluating scientific evidence of sentience, focusing on pain
experience. It includes eight neural and cognitive-behavioural criteria, with confidence …
experience. It includes eight neural and cognitive-behavioural criteria, with confidence …
Anxiety disorders and GABA neurotransmission: a disturbance of modulation
P Nuss - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
Lines of evidence coming from many branches of neuroscience indicate that anxiety
disorders arise from a dysfunction in the modulation of brain circuits which regulate …
disorders arise from a dysfunction in the modulation of brain circuits which regulate …
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
Bacterial colonisation of the intestine has a major role in the post-natal development and
maturation of the immune and endocrine systems. These processes are key factors …
maturation of the immune and endocrine systems. These processes are key factors …
Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant …
Background: Psilocybin has shown promise as a treatment for depression but its therapeutic
mechanisms are not properly understood. In contrast to the presumed actions of …
mechanisms are not properly understood. In contrast to the presumed actions of …
[HTML][HTML] Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety
Glyphosate is the active ingredient of some of the most highly produced and used herbicides
worldwide. The intensive applications of glyphosate-based herbicides and its half-life in …
worldwide. The intensive applications of glyphosate-based herbicides and its half-life in …
[HTML][HTML] Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic-and antidepressant-like effects
W Jiang, Y Zhang, L **ao… - The Journal of …, 2005 - Am Soc Clin Investig
The hippocampal dentate gyrus in the adult mammalian brain contains neural
stem/progenitor cells (NS/PCs) capable of generating new neurons, ie, neurogenesis. Most …
stem/progenitor cells (NS/PCs) capable of generating new neurons, ie, neurogenesis. Most …
P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function
AL Garcia-Garcia, A Newman-Tancredi… - …, 2014 - Springer
Abstract Rationale Serotonin (5-HT) neurotransmission is intimately linked to anxiety and
depression and a diverse body of evidence supports the involvement of the main inhibitory …
depression and a diverse body of evidence supports the involvement of the main inhibitory …
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders
Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …
experiences may provoke a variety of illnesses. Among others things, stressors promote …