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State of the evidence 2017: an update on the connection between breast cancer and the environment
JM Gray, S Rasanayagam, C Engel, J Rizzo - Environmental Health, 2017 - Springer
Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …
compelling data linking radiation and various chemicals in our environment to the current …
Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target
The aryl hydrocarbon receptor (AHR) is highly expressed in multiple organs and tissues,
and there is increasing evidence that the AHR plays an important role in cellular …
and there is increasing evidence that the AHR plays an important role in cellular …
Cytochrome P450 1 family and cancers
RE Go, KA Hwang, KC Choi - The Journal of steroid biochemistry and …, 2015 - Elsevier
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcriptional factor that
dimerizes with aryl hydrocarbon receptor nuclear translocator (ARNT). This complex binds to …
dimerizes with aryl hydrocarbon receptor nuclear translocator (ARNT). This complex binds to …
Role of aryl hydrocarbon receptor in cancer
S Feng, Z Cao, X Wang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2013 - Elsevier
Aryl hydrocarbon receptor (AHR), a cytosolic ligand-activated transcription factor, belongs to
the member of bHLH/PAS family of heterodimeric transcriptional regulators and is widely …
the member of bHLH/PAS family of heterodimeric transcriptional regulators and is widely …
The aryl hydrocarbon receptor repressor–more than a simple feedback inhibitor of AhR signaling: clues for its role in inflammation and cancer
The aryl hydrocarbon receptor repressor (AhRR) was first described as a specific
competitive repressor of aryl hydrocarbon receptor (AhR) activity based on its ability to …
competitive repressor of aryl hydrocarbon receptor (AhR) activity based on its ability to …
Endocrine disruptors and endometrial cancer: molecular mechanisms of action and clinical implications, a systematic review
D Caserta, MP De Marco, AR Besharat… - International Journal of …, 2022 - mdpi.com
It has been widely demonstrated that endocrine disruptors play a central role in various
physiopathological processes of human health. In the literature, various carcinogenic …
physiopathological processes of human health. In the literature, various carcinogenic …
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes
J Iqbal, L Sun, J Cao, T Yuen, P Lu, I Bab… - Proceedings of the …, 2013 - pnas.org
Smoking is a major risk factor for osteoporosis and fracture, but the mechanism through
which smoke causes bone loss remains unclear. Here, we show that the smoke toxins …
which smoke causes bone loss remains unclear. Here, we show that the smoke toxins …
Coffee intake, cardiovascular disease and all-cause mortality: observational and Mendelian randomization analyses in 95 000–223 000 individuals
AT Nordestgaard… - International journal of …, 2016 - academic.oup.com
Background: Coffee has been associated with modestly lower risk of cardiovascular disease
and all-cause mortality in meta-analyses; however, it is unclear whether these are causal …
and all-cause mortality in meta-analyses; however, it is unclear whether these are causal …
Chemical activation of estrogen and aryl hydrocarbon receptor signaling pathways and their interaction in toxicology and metabolism
P Tarnow, T Tralau, A Luch - Expert opinion on drug metabolism & …, 2019 - Taylor & Francis
ABSTRACT Introduction: Estrogen receptors (ERs) and the arylhydrocarbon receptor (AHR)
are ligand-activated transcription factors that regulate the expression of genes involved in …
are ligand-activated transcription factors that regulate the expression of genes involved in …
Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and …
Neuropathological changes of the hippocampus have been associated with psychotic
disorders such as schizophrenia and bipolar disorder. Recent work has particularly …
disorders such as schizophrenia and bipolar disorder. Recent work has particularly …