DHEA and DHEAS are steroids synthesized in human adrenals, but their function is unclear.
In addition to adrenal synthesis, evidence also indicates that DHEA and DHEAS are …

Corticotropin-releasing hormone (CRH) plays a central role in the regulation of the
hypothalamic-pituitary-adrenal (HPA)-axis, ie, the final common pathway in the stress …

This chapter provides an overview of neurosteroids, especially their impact on the brain, sex
differences and their therapeutic potentials. Neurosteroids are synthesized within the brain …

Studies in animals showed that stress results in damage to the hippocampus, a brain area
involved in learning and memory, with associated memory deficits. The mechanism involves …

Objectives: This study investigated the relationships between a mindfulness-based stress
reduction meditation program for early stage breast and prostate cancer patients and quality …

Dehydroepiandrosterone (DHEA) and its sulfated metabolite DHEA‐S are endogenous
hormones secreted by the adrenal cortex in response to adrenocorticotrophin (ACTH). Much …

Throughout most of their lives, women are at greater risk for depression than men.
Hormones and neurotransmitters share common pathways and receptor sites in areas of the …

Background The physiologic role of dehydroepiandrosterone in humans is still unclear.
Adrenal insufficiency leads to a deficiency of dehydroepiandrosterone; we therefore …

Impaired cognition is often overlooked in the clinical management of depression, despite its
association with poor psychosocial functioning and reduced clinical engagement. There is …

Individual differences in the aging process can be conceptualized as an accumulation of
wear and tear of daily experiences and major life stressors that interact with the genetic …