Confined fluids and electrolyte solutions in nanopores exhibit rich and surprising physics
and chemistry that impact the mass transport and energy efficiency in many important …

Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

There is an unmet need to develop low-cost, rapid and highly multiplexed diagnostic
technology platforms for quantitatively detecting blood biomarkers to advance clinical …

MicroRNAs (miRNAs) play essential roles in post-transcriptional gene expression and are
also found freely circulating in bodily fluids such as blood. Dysregulated miRNA signatures …

Fluid transport at the nanoscale is ubiquitous in nature. However, rigorous study of fluid flow
and structure in artificial nanopores only emerged relatively recently. Termed nanofluidics …

Bioinspired smart asymmetric nanochannel membranes (BSANM) have been explored
extensively to achieve the delicate ionic transport functions comparable to those of living …

Nanopores and nanochannels are ubiquitous, from biological systems to various artificial
materials. Taking advantage of size confinement and tailoring the interior components …

Monitoring and manipulating the physical and chemical behavior of single molecules is an
important development direction of molecular electronics that aids in understanding the …

Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Single-molecule detection has long relied on fluorescent labeling with high quantum-yield
fluorophores. Plasmon-enhanced detection circumvents the need for labeling by allowing …