The chemical reactivity of membrane lipids

G Duché, JM Sanderson - Chemical Reviews, 2024 - ACS Publications
It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

Plant sources, extraction methods, and uses of squalene

MA Lozano-Grande, S Gorinstein… - … journal of agronomy, 2018 - Wiley Online Library
Squalene (SQ) is a natural compound, a precursor of various hormones in animals and
sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional …

Quaternary ammonium compounds: bioaccumulation potentials in humans and levels in blood before and during the Covid-19 pandemic

G Zheng, TF Webster, A Salamova - Environmental science & …, 2021 - ACS Publications
Quaternary ammonium compounds (QACs) are commonly used in a variety of consumer,
pharmaceutical, and medical products. In this study, bioaccumulation potentials of 18 QACs …

[HTML][HTML] Rearrangements of organic peroxides and related processes

IA Yaremenko, VA Vil, DV Demchuk… - Beilstein journal of …, 2016 - beilstein-journals.org
This review is the first to collate and summarize main data on named and unnamed
rearrangement reactions of peroxides. It should be noted, that in the chemistry of peroxides …

Connecting the “dots”: from free radical lipid autoxidation to cell pathology and disease

MK Foret, R Lincoln, S Do Carmo, AC Cuello… - Chemical …, 2020 - ACS Publications
Our understanding of lipid peroxidation in biology and medicine is rapidly evolving, as it is
increasingly implicated in various diseases but also recognized as a key part of normal cell …

Lipid peroxidation: kinetics, mechanisms, and products

ZAM Zielinski, DA Pratt - The Journal of organic chemistry, 2017 - ACS Publications
Recent advances in our understanding of lipid peroxidation, a degenerative process that is
believed to play a key role in the pathogenesis of many diseases, are highlighted. In …

Enhancing 7-dehydrocholesterol suppresses brain ferroptosis and tissue injury after neonatal hypoxia–ischemia

TC Genaro-Mattos, Z Korade, N Sahar, JPF Angeli… - Scientific reports, 2024 - nature.com
Neonatal hypoxic-ischemic brain injury (HIBI) results in part from excess reactive oxygen
species and iron-dependent lipid peroxidation (ie ferroptosis). The vitamin D precursor 7 …

Differential contributions of distinct free radical peroxidation mechanisms to the induction of ferroptosis

Q Do, R Zhang, G Hooper, L Xu - JACS Au, 2023 - ACS Publications
Ferroptosis is a form of regulated cell death driven by lipid peroxidation of polyunsaturated
fatty acids (PUFAs). Lipid peroxidation can propagate through either the hydrogen-atom …

How do different lipid peroxidation mechanisms contribute to ferroptosis?

Q Do, L Xu - Cell Reports Physical Science, 2023 - cell.com
Lipid peroxidation is the driver of ferroptotic cell death. However, nonconjugated and
conjugated polyunsaturated fatty acids potentiate ferroptosis differently, while some …

Identification and Quantitation of C C Location Isomers of Unsaturated Fatty Acids by Epoxidation Reaction and Tandem Mass Spectrometry

Y Zhao, H Zhao, X Zhao, J Jia, Q Ma, S Zhang… - Analytical …, 2017 - ACS Publications
Unsaturated fatty acids (FAs) serve as nutrients, energy sources, and signaling molecules
for organisms, which are the major components for a large variety of lipids. However …