Mechanisms and disease consequences of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
Arachidonic acid metabolism and kidney inflammation
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
Lipid accumulation and chronic kidney disease
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …
An overview of lipid metabolism and nonalcoholic fatty liver disease
K Pei, T Gui, D Kan, H Feng, Y **… - BioMed Research …, 2020 - Wiley Online Library
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …
The polysaccharides from Auricularia auricula alleviate non-alcoholic fatty liver disease via modulating gut microbiota and bile acids metabolism
Y Shu, Y Huang, W Dong, X Fan, Y Sun, G Chen… - International Journal of …, 2023 - Elsevier
The polysaccharides from Auricularia auricula (AAPs), containing a large number of O-acetyl
groups that are related to the physiological and biological properties, seem to be potential …
groups that are related to the physiological and biological properties, seem to be potential …
Bile acids and their receptors: modulators and therapeutic targets in liver inflammation
A Bertolini, R Fiorotto, M Strazzabosco - Seminars in immunopathology, 2022 - Springer
Bile acids participate in the intestinal emulsion, digestion, and absorption of lipids and fat-
soluble vitamins. When present in high concentrations, as in cholestatic liver diseases, bile …
soluble vitamins. When present in high concentrations, as in cholestatic liver diseases, bile …
Update on FXR biology: promising therapeutic target?
CY Han - International journal of molecular sciences, 2018 - mdpi.com
Farnesoid X receptor (FXR), a metabolic nuclear receptor, plays critical roles in the
maintenance of systemic energy homeostasis and the integrity of many organs, including …
maintenance of systemic energy homeostasis and the integrity of many organs, including …
Nonalcoholic fatty liver disease and chronic kidney disease: epidemiology, pathogenesis, and clinical and research implications
Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic
liver disease worldwide, affecting up to~ 30% of adult populations. NAFLD defines a …
liver disease worldwide, affecting up to~ 30% of adult populations. NAFLD defines a …
Bile acid and receptors: Biology and drug discovery for nonalcoholic fatty liver disease
T Jiao, Y Ma, X Guo, Y Ye, C **e - Acta Pharmacologica Sinica, 2022 - nature.com
Nonalcoholic fatty liver disease (NAFLD), a series of liver metabolic disorders manifested by
lipid accumulation within hepatocytes, has become the primary cause of chronic liver …
lipid accumulation within hepatocytes, has become the primary cause of chronic liver …
Geniposide ameliorates liver fibrosis through reducing oxidative stress and inflammatory respose, inhibiting apoptosis and modulating overall metabolism
L Yang, L Bi, L **, Y Wang, Y Li, Z Li, W He… - Frontiers in …, 2021 - frontiersin.org
Liver fibrosis is a progressive liver damage condition caused by various factors and may
progress toward liver cirrhosis, and even hepatocellular carcinoma. Many studies have …
progress toward liver cirrhosis, and even hepatocellular carcinoma. Many studies have …