Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Animals rely on their nervous systems to process sensory inputs, integrate these with
internal signals, and produce behavioral outputs. This is enabled by the highly specialized …

One goal of modern day neuroscience is the establishment of molecular maps that assign
unique features to individual neuron types. Such maps provide important starting points for …

Animals must weigh competing needs and states to generate adaptive behavioral
responses to the environment. Sensorimotor circuits are thus tasked with integrating diverse …

Extracellular vesicles (EVs) are integral to numerous biological processes, yet it is unclear
how environmental factors or interactions among individuals within a population affect EV …

Neurons modify their transcriptomes in response to an animal's experience. How specific
experiences are transduced to modulate gene expression and precisely tune neuronal …

Biological sex, a fundamental dimension of internal state, can modulate neural circuits to
generate behavioral variation. Understanding how and why circuits are tuned by sex can …

An animal's ability to sense odors declines during aging, and its olfactory drive is tuned by
internal states such as satiety. However, whether internal states modulate an age …

Dynamic integration of internal and external cues is essential for flexible, adaptive behavior.
In C. elegans, biological sex and feeding state regulate expression of the food-associated …

Highlights•C. elegans encodes complex olfactory behaviors with only a small number of
neurons.•Microcircuit motifs that are fundamental across computational systems encode …