Homologous recombination (HR) serves to eliminate deleterious lesions, such as double-
stranded breaks and interstrand crosslinks, from chromosomes. HR is also critical for the …

Homologous recombination (HR) is critical both for repairing DNA lesions in mitosis and for
chromosomal pairing and exchange during meiosis. However, some forms of HR can also …

Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …

The budding yeast Saccharomyces cerevisiae has been the principal organism used in
experiments to examine genetic recombination in eukaryotes. Studies over the past decade …

▪ Abstract Meiotic chromosomes have been studied for many years, in part because of the
fundamental life processes they represent, but also because meiosis involves the formation …

Homologous recombination (HR) is an important mechanism for the repair of damaged
chromosomes, for preventing the demise of damaged replication forks, and for several other …

The process of homologous recombination is a major DNA repair pathway that operates on
DNA double-strand breaks, and possibly other kinds of DNA lesions, to promote error-free …

Homology search and DNA strand–exchange reactions are central to homologous
recombination in meiosis. During meiosis, these processes are regulated such that the …

Homologous recombination is essential during meiosis in most sexually reproducing
organisms. In budding yeast, and most likely in other organisms as well, meiotic …

Meiosis is a special type of cell division that produces haploid gametes from diploid parental
cells. Chromosome number is reduced during meiosis because a single round of DNA …