Background Clinical research affecting how doctors practice medicine is increasingly
sponsored by companies that make drugs and medical devices. Previous systematic …

The preceding papers in this Series have outlined how underuse and overuse of health-care
services occur within a complex system of health-care production, with a multiplicity of …

A practical guide to network meta-analysis with examples and code In the evaluation of
healthcare, rigorous methods of quantitative assessment are necessary to establish which …

The global ubiquity of overuse and underuse of health-care resources and the gravity of
resulting harms necessitate an investigation of drivers to inform potential solutions. We …

Objectives To provide recommendations for the selection of comparators for randomized
controlled trials of health-related behavioral interventions. Study Design and Setting The …

Importance Randomized clinical trials (RCTs) provide the highest level of evidence to
evaluate 2 or more surgical interventions. Surgical RCTs, however, face unique challenges …

Purpose Clinical research is widely sponsored by drug and device companies. We
investigated whether industry sponsored drug and device studies have more favorable …

Objective To assess the benefits and harms of pregabalin in the management of neuropathic
pain. Design Rapid review and meta-analysis of phase III, randomised, placebo-controlled …

Breastfeeding and human milk (HM) are critically important to maternal, infant and
population health. This paper summarizes the proceedings of a workshop that convened a …

Value-Based Health Care at an Inflection Point: A Global Agenda for the Next Decade Page 1
COMMENTARY A growing number of health care organizations around the world are using the …