Antimicrobial peptides: Their role as infection‐selective tracers for molecular imaging
Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …
of organisms including humans and, so far, hundreds of these structures have been isolated …
Bifunctional gallium-68 chelators: Past, present, and future
P Spang, C Herrmann, F Roesch - Seminars in nuclear medicine, 2016 - Elsevier
This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …
radiopharmaceuticals. It structures the chelates into groups of macrocycles …
A decade of ubiquicidin development for PET imaging of infection: a systematic review
Background Ubiquicidin is a peptide fragment with selective binding to negatively charged
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …
Selectivity of antimicrobial peptides: a complex interplay of multiple equilibria
S Bobone, L Stella - Antimicrobial Peptides: Basics for Clinical Application, 2019 - Springer
Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
Development of a Single Vial Kit Solution for Radiolabeling of 68Ga-DKFZ-PSMA-11 and Its Performance in Prostate Cancer Patients
Prostate-specific membrane antigen (PSMA), a type II glycoprotein, is highly expressed in
almost all prostate cancers. By playing such a universal role in the disease, PSMA provides …
almost all prostate cancers. By playing such a universal role in the disease, PSMA provides …
Continued rapid growth in 68Ga applications: update 2013 to June 2014
I Velikyan - Journal of Labelled Compounds and …, 2015 - Wiley Online Library
The worldwide utilization of 68Ga‐radionuclide for the fundamental research and clinical
applications is growing exponentially. A broad range of 68Ga‐based imaging agents has …
applications is growing exponentially. A broad range of 68Ga‐based imaging agents has …
Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation
I Velikyan - Contrast Media & Molecular Imaging, 2018 - Wiley Online Library
During the last decade, the utilization of 68Ga for the development of imaging agents has
increased considerably with the leading position in the oncology. The imaging of infection …
increased considerably with the leading position in the oncology. The imaging of infection …
68Ga-NOTA-functionalized ubiquicidin: cytotoxicity, biodistribution, radiation dosimetry, and first-in-human PET/CT imaging of infections
Ubiquicidin is an antimicrobial peptide with great potential for nuclear imaging of infectious
diseases, as its cationic-rich fragment TGRAKRRMQYNRR (UBI) has been functionalized …
diseases, as its cationic-rich fragment TGRAKRRMQYNRR (UBI) has been functionalized …
68Ga-NOTA-UBI-29-41 as a PET tracer for detection of bacterial infection
M Vilche, AL Reyes, E Vasilskis, P Oliver… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The cationic peptide 68Ga-NOTA-UBI-29-41 was synthesized and characterized.
Biodistribution and PET/CT examinations were performed for evaluation of its biologic …
Biodistribution and PET/CT examinations were performed for evaluation of its biologic …
Monitoring response to therapy
Monitoring response to treatment is a key element in the management of infectious
diseases, yet controversies still persist on reliable biomarkers for noninvasive response …
diseases, yet controversies still persist on reliable biomarkers for noninvasive response …