Bacterial biofilm formation on biomaterials and approaches to its treatment and prevention

P Li, R Yin, J Cheng, J Lin - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial biofilms can cause widespread infection. In addition to causing urinary tract
infections and pulmonary infections in patients with cystic fibrosis, biofilms can help …

Titanium for orthopedic applications: an overview of surface modification to improve biocompatibility and prevent bacterial biofilm formation

J Quinn, R McFadden, CW Chan, L Carson - IScience, 2020 - cell.com
Titanium and its alloys have emerged as excellent candidates for use as orthopedic
biomaterials. Nevertheless, there are often complications arising after implantation of …

Biofilm antimicrobial susceptibility testing: where are we and where could we be going?

T Coenye - Clinical microbiology reviews, 2023 - Am Soc Microbiol
Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

[HTML][HTML] Microbial resistance to nanotechnologies: An important but understudied consideration using antimicrobial nanotechnologies in orthopaedic implants

Z Wu, B Chan, J Low, JJH Chu, HWD Hey, A Tay - Bioactive Materials, 2022 - Elsevier
Microbial resistance to current antibiotics therapies is a major cause of implant failure and
adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced …

Surficial nano-deposition locoregionally yielding bactericidal super CAR-macrophages expedites periprosthetic osseointegration

Z Li, S Zhang, Z Fu, Y Liu, Z Man, C Shi, C Tang… - Science …, 2023 - science.org
Tracking and eradicating Staphylococcus aureus in the periprosthetic microenvironment are
critical for preventing periprosthetic joint infection (PJI), yet effective strategies remain …

Twenty common errors in the diagnosis and treatment of periprosthetic joint infection

C Li, N Renz, A Trampuz, C Ojeda-Thies - International orthopaedics, 2020 - Springer
Background Misconceptions and errors in the management of periprosthetic joint infection
(PJI) can compromise the treatment success. The goal of this paper is to systematically …

Recent advances in research on antibacterial metals and alloys as implant materials

J Jiao, S Zhang, X Qu, B Yue - Frontiers in cellular and infection …, 2021 - frontiersin.org
Implants are widely used in orthopedic surgery and are gaining attention of late. However,
their use is restricted by implant-associated infections (IAI), which represent one of the most …

Silver-coated megaprosthesis in prevention and treatment of peri-prosthetic infections: A systematic review and meta-analysis about efficacy and toxicity in primary …

M Fiore, A Sambri, R Zucchini, C Giannini… - European Journal of …, 2021 - Springer
Aim Prosthetic joint infection (PJI) is a common complication following orthopedic
megaprosthetic implantations (EPR), estimated up to 50%. Silver coatings were introduced …

Chitosan and hydroxyapatite based biomaterials to circumvent periprosthetic joint infections

AR Costa-Pinto, AL Lemos, FK Tavaria, M Pintado - Materials, 2021 - mdpi.com
Every year, worldwide, millions of people suffering from joint pain undergo joint
replacement. For most patients, joint arthroplasty reduces pain and improve function, though …

Recent advances in bio-functional Ta-based bone materials: materials design and bioactivity

MY Wu, M Zhao, Y Cai, JG Yao, P Wang… - International Journal of …, 2024 - iopscience.iop.org
Ta-based materials have gained significant interest for bioimplantable scaffolds because of
their appropriate mechanical characteristics and biocompatibility. To overcome the serious …