Controversies around epithelial–mesenchymal plasticity in cancer metastasis

ED Williams, D Gao, A Redfern… - Nature Reviews Cancer, 2019 - nature.com
Experimental evidence accumulated over decades has implicated epithelial–mesenchymal
plasticity (EMP), which collectively encompasses epithelial–mesenchymal transition and the …

The oral microbiome and cancer

M Irfan, RZR Delgado, J Frias-Lopez - Frontiers in immunology, 2020 - frontiersin.org
There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …

Role of oral microbiome signatures in diagnosis and prognosis of oral cancer

I Chattopadhyay, M Verma… - Technology in cancer …, 2019 - journals.sagepub.com
Despite advancement in cancer treatment, oral cancer has a poor prognosis and is often
detected at late stage. To overcome these challenges, investigators should search for early …

Oral mucosal epithelial cells

S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …

Association between periodontal disease and atherosclerotic cardiovascular diseases: revisited

F Zardawi, S Gul, A Abdulkareem, A Sha… - Frontiers in …, 2021 - frontiersin.org
Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary
arteries associated with atheroma formation, which can cause disability and often death …

Role of Porphyromonas gingivalis in oral and orodigestive squamous cell carcinoma

RJ Lamont, ZR Fitzsimonds, H Wang… - Periodontology …, 2022 - Wiley Online Library
Oral and esophageal squamous cell carcinomas harbor a diverse microbiome that differs
compositionally from precancerous and healthy tissues. Though causality is yet to be …

Porphyromonas gingivalis and Its Systemic Impact: Current Status

F Mei, M **e, X Huang, Y Long, X Lu, X Wang, L Chen - Pathogens, 2020 - mdpi.com
The relationship between periodontitis and systemic diseases, notably including
atherosclerosis and diabetes, has been studied for several years. Porphyromonas …

Chronic inflammation as a link between periodontitis and carcinogenesis

A Hoare, C Soto, V Rojas-Celis… - Mediators of …, 2019 - Wiley Online Library
Periodontitis is characterized by a chronic inflammation produced in response to a disease‐
associated multispecies bacterial community in the subgingival region. Although the …

Possible role of Porphyromonas gingivalis in orodigestive cancers

I Olsen, Ö Yilmaz - Journal of oral microbiology, 2019 - Taylor & Francis
There is increasing evidence for an association between periodontitis/tooth loss and oral,
gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by …

Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H **a, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …