Centenarians represent a phenomenon of successful aging. This systematic review aimed to
understand lifestyles and health practices, focusing on diet and medication use for healthy …

Oxidative stress is involved in age‐related cognitive decline. The dietary antioxidants,
carotenoids, tocopherols, and vitamin A may play a role in the prevention or delay in …

Purpose of the Study: This research integrates successful aging and developmental
adaptation models to empirically define the direct and indirect effects of 2 distal (ie …

Background The overall impact of social connectedness on health outcomes in older adults
living in nursing homes and assisted living settings is unknown. Given the unclear health …

Hippocampal sclerosis is a relatively common neuropathological finding (∼ 10% of
individuals over the age of 85 years) characterized by cell loss and gliosis in the …

The purpose of this study was to evaluate the relationship between physical health and
psychological well‐being among oldest‐old adults. Structural equation modeling was …

Many countries are witnessing a marked increase in longevity and with this increased
lifespan and the desire for healthy ageing, many, however, suffer from the opposite including …

With an emphasis on evolving concepts in the field, we evaluated neuropathologic data from
very old research volunteers whose brain autopsies were performed at the University of …

A targeted therapy (TT) refers to a type of treatment that uses drugs or other substances to
identify and attack specific types of cancer cells with less harm to normal cells by targeting …

Importance Some individuals who reach ages beyond 100 years in good cognitive health
may be resilient against risk factors associated with cognitive decline. Exploring the …