Metagenomic data assembly–the way of decoding unknown microorganisms
AL Lapidus, AI Korobeynikov - Frontiers in Microbiology, 2021 - frontiersin.org
Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …
sequencing and analysis of combined genomic DNA of entire environmental samples. The …
New approaches for metagenome assembly with short reads
In recent years, the use of longer range read data combined with advances in assembly
algorithms has stimulated big improvements in the contiguity and quality of genome …
algorithms has stimulated big improvements in the contiguity and quality of genome …
Assembling large genomes with single-molecule sequencing and locality-sensitive hashing
Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …
microbial genomes, but available assembly methods have not scaled well to larger …
Healthy human gut phageome
The role of bacteriophages in influencing the structure and function of the healthy human gut
microbiome is unknown. With few exceptions, previous studies have found a high level of …
microbiome is unknown. With few exceptions, previous studies have found a high level of …
Bacteriophage targeting microbiota alleviates non-alcoholic fatty liver disease induced by high alcohol-producing Klebsiella pneumoniae
L Gan, Y Feng, B Du, H Fu, Z Tian, G Xue… - Nature …, 2023 - nature.com
Our previous studies have shown that high alcohol-producing Klebsiella pneumoniae (HiAlc
Kpn) in the intestinal microbiome could be one of the causes of non-alcoholic fatty liver …
Kpn) in the intestinal microbiome could be one of the causes of non-alcoholic fatty liver …
Extremely high mutation rate of HIV-1 in vivo
Rates of spontaneous mutation critically determine the genetic diversity and evolution of
RNA viruses. Although these rates have been characterized in vitro and in cell culture …
RNA viruses. Although these rates have been characterized in vitro and in cell culture …
SARS‐CoV‐2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID‐19 vaccination
In Denmark, vaccination against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS‐
CoV‐2) has been with the Pfizer‐BioNTech (BTN162b2) or the Moderna (mRNA‐1273) …
CoV‐2) has been with the Pfizer‐BioNTech (BTN162b2) or the Moderna (mRNA‐1273) …
An introduction to next generation sequencing bioinformatic analysis in gut microbiome studies
The gut microbiome is a microbial ecosystem which expresses 100 times more genes than
the human host and plays an essential role in human health and disease pathogenesis …
the human host and plays an essential role in human health and disease pathogenesis …
Technology dictates algorithms: recent developments in read alignment
Aligning sequencing reads onto a reference is an essential step of the majority of genomic
analysis pipelines. Computational algorithms for read alignment have evolved in …
analysis pipelines. Computational algorithms for read alignment have evolved in …
Characterization of a novel orthomyxo-like virus causing mass die-offs of tilapia
Tilapia are an important global food source due to their omnivorous diet, tolerance for high-
density aquaculture, and relative disease resistance. Since 2009, tilapia aquaculture has …
density aquaculture, and relative disease resistance. Since 2009, tilapia aquaculture has …