Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

Sensory feedback for limb prostheses in amputees

S Raspopovic, G Valle, FM Petrini - Nature Materials, 2021 - nature.com
Commercial prosthetic devices currently do not provide natural sensory information on the
interaction with objects or movements. The subsequent disadvantages include …

A brain-computer interface that evokes tactile sensations improves robotic arm control

SN Flesher, JE Downey, JM Weiss, CL Hughes… - Science, 2021 - science.org
Prosthetic arms controlled by a brain-computer interface can enable people with tetraplegia
to perform functional movements. However, vision provides limited feedback because …

Restoration of sensory information via bionic hands

SJ Bensmaia, DJ Tyler, S Micera - Nature Biomedical Engineering, 2023 - nature.com
Individuals who have lost the use of their hands because of amputation or spinal cord injury
can use prosthetic hands to restore their independence. A dexterous prosthesis requires the …

Neurorobotic fusion of prosthetic touch, kinesthesia, and movement in bionic upper limbs promotes intrinsic brain behaviors

PD Marasco, JS Hebert, JW Sensinger, DT Beckler… - Science robotics, 2021 - science.org
Bionic prostheses have restorative potential. However, the complex interplay between
intuitive motor control, proprioception, and touch that represents the hallmark of human …

Biomimetic sensory feedback through peripheral nerve stimulation improves dexterous use of a bionic hand

JA George, DT Kluger, TS Davis, SM Wendelken… - Science Robotics, 2019 - science.org
We describe use of a bidirectional neuromyoelectric prosthetic hand that conveys
biomimetic sensory feedback. Electromyographic recordings from residual arm muscles …

Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain

LE Osborn, A Dragomir, JL Betthauser, CL Hunt… - Science robotics, 2018 - science.org
The human body is a template for many state-of-the-art prosthetic devices and sensors.
Perceptions of touch and pain are fundamental components of our daily lives that convey …

Implantable intracortical microelectrodes: reviewing the present with a focus on the future

Y Wang, X Yang, X Zhang, Y Wang… - Microsystems & …, 2023 - nature.com
Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Biomimetic intraneural sensory feedback enhances sensation naturalness, tactile sensitivity, and manual dexterity in a bidirectional prosthesis

G Valle, A Mazzoni, F Iberite, E D'Anna, I Strauss… - Neuron, 2018 - cell.com
Peripheral intraneural stimulation can provide tactile information to amputees. However,
efforts are still necessary to identify encoding strategy eliciting percepts that are felt as both …

Neuroprosthetics: from sensorimotor to cognitive disorders

A Gupta, N Vardalakis, FB Wagner - Communications biology, 2023 - nature.com
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …