Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Strategies for delivering therapeutics across the blood–brain barrier

GC Terstappen, AH Meyer, RD Bell… - Nature Reviews Drug …, 2021 - nature.com
Achieving sufficient delivery across the blood–brain barrier is a key challenge in the
development of drugs to treat central nervous system (CNS) disorders. This is particularly …

Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

[HTML][HTML] Current strategies to enhance delivery of drugs across the blood–brain barrier

RI Teleanu, MD Preda, AG Niculescu, O Vladâcenco… - Pharmaceutics, 2022 - mdpi.com
The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

[HTML][HTML] Multiple nano-drug delivery systems for intervertebral disc degeneration: current status and future perspectives

W Liu, Z Ma, Y Wang, J Yang - Bioactive materials, 2023 - Elsevier
Low back pain (LBP) is a common disease that imposes a huge social and economic
burden on people. Intervertebral disc (IVD) degeneration (IVDD) is often considered to be …

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of controlled release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

[HTML][HTML] Applications of nanotechnology in drug delivery to the central nervous system

M Saeedi, M Eslamifar, K Khezri, SM Dizaj - Biomedicine & …, 2019 - Elsevier
In recent years, the researchers and drug designers have given growing attention to new
nanotechnology strategies to improve drug delivery to the central nervous system (CNS) …

Therapeutic applications of terpenes on inflammatory diseases

ML Del Prado-Audelo, H Cortés… - Frontiers in …, 2021 - frontiersin.org
In the last decades, the search for natural products with biological applications as alternative
treatments for several inflammatory diseases has increased. In this respect, terpenes are a …

[PDF][PDF] Emulsion micro emulsion and nano emulsion: a review

SN Kale, SL Deore - Systematic Reviews in Pharmacy, 2017 - unique-therapeutics.com
Lipid dosage forms are attractive delivery systems for hydrophobic drug molecules.
Emulsion is one of the popular system since many decades. Pharmaceutical applications of …